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Q-onset ventricular depolarization detection in the presence of a pacemaker

  • US 9,986,926 B2
  • Filed: 10/22/2008
  • Issued: 06/05/2018
  • Est. Priority Date: 10/26/2007
  • Status: Active Grant
First Claim
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1. A method employable in the presence of an operating pacemaker for determining the true onset of ventricular depolarization in a subject'"'"'s cardiac cycles comprisingduring a selected, predetermined time span which includes a plurality of the subject'"'"'s cardiac cycles, acquiring, externally, EGC waveform data reflected in those cycles,gathering, solely from within such acquired data, and with respect to each included cardiac cycle represented in that data, electrical-event waveform information respecting the two, potential, true-onset event candidates—

  • QRS-intrinsic, and pacemaker-non-intrinsic, and,in relation to the gathered, QRS-intrinsic and pacemaker-non-intrinsic, electrical event waveform information, for each cycle in the mentioned plurality of cycles, andutilizing an appropriately programmed computer, identifying which of the QRS-intrinsic and pacemaker-non-intrinsic events present in the cycle is to be determined as being the one reflecting true ventricular-depolarization onset through(a) time-locating, time-position-sorting, and identifying as first-in-time and last-in-time, the respective events in the cycle of a QRS-intrinsic event and of a pacemaker-non-intrinsic event, and identifying, further, each pacemaker-non-intrinsic event as being one of ventricular or bi-ventricular,(b) evaluating, in the gathered waveform information associated with the cycle, the waveform slope therein from a time just preceding the identified first-in-time event to a time just following the identified last-in-time event,(c) based on said evaluating, finding the time of the first substantial waveform slope change, and(d) selecting to be the correct event in the cycle which reflects true ventricular depolarization onset the time-position-sorted event whose time position in the cycle most immediately precedes the time of the found, first-substantial slope change.

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