Vascular elastance

• US 9,987,153 B2
• Filed: 05/31/2011
• Issued: 06/05/2018
• Est. Priority Date: 06/08/2010
• Status: Active Grant

• Current Assignee: Regents of The University of Minnesota (University of Minnesota)
• Original Assignee: Regents of The University of Minnesota (University of Minnesota)
• Inventors: Scandurra, John, Vollmers, Karl, Scorzelli, Christopher, Little, Eric F.
• Primary Examiner(s): Prone, Christopher D
• Assistant Examiner(s): Diop, Rokhaya
• Application Number:
  US13/701,721
• Publication Number:
  US 20130079871A1
• Time in Patent Office: 2,562 Days
• Field of Search: 623 112, 623 113, 623 114, 623 125, 623 2367, 606191, 606192, 606194
• CPC Class Codes: A61B 17/12036 partial occlusion
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61F 2/06 Blood vessels
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/848 having means for fixation to the vessel wall, e.g. barbs
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2230/0065 toroidal, e.g. ring-shaped, doughnut-shaped
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61F 2250/0013 for adjusting fluid pressure

Abstract

A device includes a balloon and an interface. The balloon has an outer surface and a central lumen aligned on a longitudinal axis. The balloon is configured to receive a compressible fluid. The interface is coupled to the outer surface and has an external surface configured to bond with a tissue.

Claims

1. A device configured to be implanted in a pulmonary artery to treat pulmonary hypertension, the device comprising:

a balloon having an outer surface and a cylindrical shape, the balloon sized and shaped to be fully implanted within the pulmonary artery and configured to receive a compressible fluid;

an interface sized and shaped to be fully implanted within the pulmonary artery and configured to expand upon deployment to intimately contact a wall of the pulmonary artery, the interface configured to be coupled to the balloon so that the balloon is suspended within a lumen of the pulmonary artery such that the balloon compresses under positive differential pressure where blood is permitted to flow between the outer surface of the balloon and an inner surface of the wall of the pulmonary artery, the balloon further configured to return to an original, expanded position under negative differential pressure where blood is permitted to flow between the outer surface of the balloon and the inner surface of the wall of the pulmonary artery, the interface having an external surface configured to bond with the wall of the pulmonary artery; and

a coating disposed on the balloon to limit diffusion of the compressible fluid through the balloon.

2. The device of claim 1, wherein the interface is aligned with a longitudinal axis of the balloon.

3. The device of claim 1, wherein the interface includes at least one of a scaffold or stent.

4. The device of claim 1, wherein the external surface is configured to enable endothelial cell development.

5. The device of claim 1, wherein the interface is configured to provide a fluid-tight joint with the wall of the pulmonary artery.

6. The device of claim 1, wherein the interface comprises a metal mesh.

7. The device of claim 1, wherein the interface comprises a non-metal mesh.

8. The device of claim 1, wherein the balloon is configured to deform such that an equivalent volume of blood occupies a space in the pulmonary artery adjacent the balloon.

9. A balloon configured for inflation using a compressible gas in a pulmonary artery to treat pulmonary hypertension, the balloon comprising an outer surface configured for affixation within a wall of the pulmonary artery and a coating configured to limit diffusion of the compressible gas through the balloon;

and

an interface configured to be coupled to the balloon and to expand upon deployment to intimately contact the wall of the pulmonary artery,

wherein the balloon is configured to be fully implanted within the pulmonary artery and to compress under positive differential pressure where blood is permitted to flow between the outer surface of the balloon and the wall of the pulmonary artery, the balloon further configured to return to an original, expanded position under negative differential pressure where blood is permitted to flow between the outer surface of the balloon and the wall of the pulmonary artery.