Injectable drug delivery arrangement with controlled delivery cannula position relative to point of delivery
First Claim
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1. A method of delivering a medicine to a target location, the method comprising:
- positioning a distal end of a cannula for insertion into a first tissue, the cannula including a steel tube defining a proximal end and the distal end of the cannula and a nodule welded along an outer circumferential surface of the steel tube and spaced at a defined distance from the distal end, the steel tube having a constant circular cross-section defining a circumference and a lumen extending between the proximal and distal ends, said nodule extending less than about the entire circumference of the tube,inserting the distal end of the cannula into the first tissue,advancing a portion of the tube through the first tissue,penetrating the nodule through the first tissue while advancing the tube through the first tissue,continuing to advance the tube through the first tissue to position the distal end of the cannula for insertion into the target location,inserting the distal end of the cannula into the target location, a depth of insertion into the target location limited by the nodule, anddelivering the medicine to the target location through the lumen.
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Abstract
A cannula for administration of a medicine to a target location includes a tube with at least one nodule disposed along the circumferential surface and spaced at a defined distance from the distal end of the tube. An arrangement for delivery of a medicine to a target location includes the cannula and a pump fluidly coupled to the cannula. The distal end of the cannula may be inserted into a target location until the nodule reaches a surface that limits a depth of penetration before delivery of the medication.
18 Citations
17 Claims
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1. A method of delivering a medicine to a target location, the method comprising:
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positioning a distal end of a cannula for insertion into a first tissue, the cannula including a steel tube defining a proximal end and the distal end of the cannula and a nodule welded along an outer circumferential surface of the steel tube and spaced at a defined distance from the distal end, the steel tube having a constant circular cross-section defining a circumference and a lumen extending between the proximal and distal ends, said nodule extending less than about the entire circumference of the tube, inserting the distal end of the cannula into the first tissue, advancing a portion of the tube through the first tissue, penetrating the nodule through the first tissue while advancing the tube through the first tissue, continuing to advance the tube through the first tissue to position the distal end of the cannula for insertion into the target location, inserting the distal end of the cannula into the target location, a depth of insertion into the target location limited by the nodule, and delivering the medicine to the target location through the lumen. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method of delivering a medicine to an inner ear, the method comprising:
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advancing a distal end of a cannula through an ear canal, the cannula including a tube defining a proximal end and the distal end of the cannula and a nodule along an outer circumferential surface of the tube and spaced at a defined distance from the distal end, the tube having a lumen extending between the proximal and distal ends, said nodule extending less than about an entire circumference of the tube, positioning the distal end of the cannula for insertion into a tympanic membrane, inserting the distal end of the cannula into the tympanic membrane, advancing a portion of the tube through the tympanic membrane, penetrating the nodule through the tympanic membrane while advancing the tube through the tympanic membrane, continuing to advance the tube through the tympanic membrane to position the distal end of the cannula for insertion into an inner ear target location, inserting the distal end of the cannula into the inner ear target location, advancing the distal end into the inner ear target location until the nodule limits a depth of penetration into the inner ear target location, and delivering the medicine to the inner ear target location through the lumen. - View Dependent Claims (15, 16, 17)
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Specification