Rotation resistant friction adapter for plunger driver of drug delivery device

• US 9,987,432 B2
• Filed: 09/22/2015
• Issued: 06/05/2018
• Est. Priority Date: 09/22/2015
• Status: Active Grant

• Current Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Original Assignee: West Pharma. Services IL, Ltd. (West Pharmaceutical Services Incorporated)
• Inventors: Cabiri, Oz, Hezkiahu, Ran
• Primary Examiner(s): Bouchelle, Laura
• Assistant Examiner(s): Ahmed, Tasnim M
• Application Number:
  US14/861,478
• Publication Number:
  US 20170080158A1
• Time in Patent Office: 987 Days
• CPC Class Codes: A61M 2005/3123 having air entrapping or venting means, e.g. purging channels in pistons
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/31501 Means for blocking or restricting the movement of the rod or piston A61M5/5013 takes precedence
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31515 Connection of piston with piston rod
• CPC Class Codes: A61M 5/31565 Administration mechanisms, i.e. constructional features, modes of administering a dose dosing mechanisms for setting a dose A61M5/31533
• CPC Class Codes: A61M 5/31583 based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
• CPC Class Codes: A61M 5/31586 performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle

Abstract

A method and system are disclosed for driving a plunger in a drug reservoir. In some embodiments, a variable friction element interconnects between a pushing shaft and a wall of the reservoir. For example, rotation of a driving element in a first direction relative to the pushing shaft may advance the pushing shaft in the reservoir. The friction element may have increased friction resistance to rotation of the pushing shaft in the first direction in comparison to frictional resistance to advancing the pushing shaft. For example, the increased friction may result from wedging a radial element between the pushing shaft and the wall of the reservoir.

Claims

1. An assembly for driving a plunger in a drug reservoir, the plunger dividing between a drug in a distal portion of the reservoir and a proximal opening of the reservoir;

the assembly comprising;

a telescoping shaft that extends by rotation of a driving element in a first rotational direction with respect to a distal shaft;

a distal end of said distal shaft configured to engage the plunger; and

an anisotropic friction element extending from said distal shaft, said friction element comprising a disk and a plurality of independent radial elements extending radially from the disk to contact an interior side wall of the reservoir, said radial elements extending from the disk toward the first rotational direction to wedge between said interior wall and said distal shaft when said distal shaft is rotated in said first rotational direction, said radial elements having respective leading edges and trailing edges, at least one of the leading edges extending radially from the disk at a first angle and a trailing edge associated with a same radial element as the at least one of the leading edges extending radially from the disk at a second angle, the first angle being steeper than the second angle.

2. The assembly of claim 1, wherein each radial element includes a virtual sprag having a long axis and wherein said long axis intersects said interior side wall.

3. The assembly of claim 1, further comprising:

a plunger interface configured to engage the plunger;

said plunger interface rotationally linking said distal shaft and the plunger when said plunger interface is engaged to the plunger.

4. The assembly of claim 1, further comprising:

a vent for releasing gas from a space between the friction element and the plunger.

5. The assembly of claim 1, wherein said friction element is located proximal to said distal end of said distal shaft.

6. The assembly of claim 1, wherein said wedging is longitudinal such that moving said distal shaft distally with respect to said reservoir reduces a normal force between said friction element and said interior wall.

7. The assembly of claim 1, wherein a resistance to movement of said distal shaft in said first rotational direction due to friction between said friction element and said interior wall is higher than a resistance to movement of said distal shaft in a direction opposite said first rotational direction due to friction between said friction element and said interior wall.

8. The assembly of claim 1, further comprising:

a second friction element extending from a drug delivery device to contact an exterior side wall of the reservoir when said reservoir is inserted into said drug delivery device, said second friction element is configured and oriented to wedge between said exterior wall and said reservoir when said reservoir is rotated in a second rotational direction.

9. The assembly of claim 8, wherein said second rotational direction is opposite said first rotational direction.

10. The assembly of claim 1, wherein each radial element defines a radially central end and a radially outer end, the radially outer end of at least one radial element being wider than the corresponding radially central end thereof.

11. A method of advancing a plunger in a drug reservoir comprising:

Providing a telescoping assembly that extends by rotating a driver in a first rotational direction with respect to a pushing shaft mated to the driver, said pushing shaft including an anisotropic friction element in contact with a wall of the reservoir, said friction element comprising a disk and a plurality of independent radial elements extending radially from the disk, said radial elements having respective leading edges and trailing edges, at least one of the leading edges extending radially from the disk at a first angle and a trailing edge associated with a same radial element as the at least one of the leading edges extending radially from the disk at a second angle, the first angle being steeper than the second angle;

rotating said driver in said first rotational direction;

wedging said friction element between said pushing shaft and said wall as result of said rotating;

inhibiting rotation of said pushing shaft as a result of said wedging; and

unwedging said friction element to facilitate advancing of said pushing shaft.

12. The method of claim 11, wherein said wedging is substantially the only inhibiting of rotation of said pushing shaft with respect to the reservoir.

13. The method of claim 11, wherein said wedging increases a force normal to said wall and said pushing shaft relative to the normal force prior to the wedging.

14. The method of claim 12, further comprising:

reducing a normal force between said friction element and said wall of the reservoir when said pushing shaft moves in a distal direction.

15. The method of claim 11, wherein the drug reservoir includes a plunger, the method further comprising:

reducing a normal force between said friction element and said wall of the reservoir when said pushing shaft pushes distally against said plunger.