Methods, systems, and devices relating to open microfluidic channels
First Claim
1. A medical device for collection of fluid from a patient comprising:
- a. a cylindrical housing having proximal and distal ends, the housing comprising defining a lumen;
b. a plunger, the plunger disposed within the lumen and comprising a distal plunger face comprising a plurality of lancets;
c. at least one fluid collection sites disposed defined within the distal housing end; and
d. a microfluidic network disposed within the lumen and in fluidic communication with the at least one fluid collection sites, the microfluidic network comprising a first open channel comprising;
i. a top portion comprising a first free surface defined by the top portion defining a first free perimeter; and
ii. a first wetted surface defining a first wetted perimeter, wherein the first wetted surface contacts fluid flowing through the first open channel at a first contact angle,wherein the ratio of the first free perimeter to the first wetted perimeter is less than the cosine of the first contact angle, thereby enabling spontaneous capillary flow through the first open channel.
1 Assignment
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Accused Products
Abstract
The various embodiments described herein relate to fabricating and using open microfluidic networks according to methods, systems, and devices that can be used in applications ranging from home-testing, diagnosis, and research laboratories. Open microfluidic networks allow the input, handling, and extraction of fluids or components of the fluid into or out of the open microfluidic network. Fluids can be inserted into an open microfluidic channel by using open sections of the open microfluidic network. Passive valves can be created in the microfluidic network, allowing the creation of logic circuits and conditional flow and volume valves. The fluid can be presented via the microfluidic network to diagnostic and analysis components. Fluids and components of the fluid can be extracted from the open microfluidic network via functional open sections that are easily interfaced with other microfluidic networks or common laboratory tools.
51 Citations
9 Claims
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1. A medical device for collection of fluid from a patient comprising:
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a. a cylindrical housing having proximal and distal ends, the housing comprising defining a lumen; b. a plunger, the plunger disposed within the lumen and comprising a distal plunger face comprising a plurality of lancets; c. at least one fluid collection sites disposed defined within the distal housing end; and d. a microfluidic network disposed within the lumen and in fluidic communication with the at least one fluid collection sites, the microfluidic network comprising a first open channel comprising; i. a top portion comprising a first free surface defined by the top portion defining a first free perimeter; and ii. a first wetted surface defining a first wetted perimeter, wherein the first wetted surface contacts fluid flowing through the first open channel at a first contact angle, wherein the ratio of the first free perimeter to the first wetted perimeter is less than the cosine of the first contact angle, thereby enabling spontaneous capillary flow through the first open channel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification