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Aromatic-cationic peptides and methods for using same

  • US 9,988,422 B2
  • Filed: 09/28/2012
  • Issued: 06/05/2018
  • Est. Priority Date: 09/29/2011
  • Status: Active Grant
First Claim
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1. A method for therapeutic treatment of atherosclerotic renal artery stenosis in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a peptide D-Arg-2′

  • ,6′

    -Dmt-Lys-Phe-NH2 or a pharmaceutically acceptable salt thereof, and further comprising the step of performing a revascularization procedure on the subject, wherein the revascularization procedure comprises administration of one or more thrombolytic agents, and wherein the subject is administered the peptide prior to onset of renal microvasculature rarefaction.

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