Apparatus and method for identifying atrial arrhythmia by far-field sensing

• US 9,993,653 B2
• Filed: 11/14/2016
• Issued: 06/12/2018
• Est. Priority Date: 11/21/2001
• Status: Expired due to Fees

• Current Assignee: Cameron Incorporated (Schlumberger NV)
• Original Assignee: Cameron Incorporated (Schlumberger NV)
• Inventors: Bardy, Gust H., Rissmann, William J., Ostroff, Alan H., Erlinger, Paul J., Allavatam, Venugopal
• Primary Examiner(s): GETZOW, SCOTT M
• Application Number:
  US15/350,574
• Publication Number:
  US 20170056681A1
• Time in Patent Office: 575 Days
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/361 Detecting fibrillation
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting
• CPC Class Codes: A61N 1/3931 Protecting, e.g. back-up systems
• CPC Class Codes: A61N 1/395 for treating atrial fibrillation
• CPC Class Codes: A61N 1/3956 Implantable devices for applying electric shocks to the heart, e.g. for cardioversion
• CPC Class Codes: A61N 1/3987 characterised by the timing or triggering of the shock

Abstract

In a subcutaneous implantable cardioverter/defibrillator, cardiac arrhythmias are detected to determine necessary therapeutic action. Cardiac signal information is sensed from far field electrodes implanted in a patient. The sensed cardiac signal information is then amplified and filtered. Parameters such as rate, QRS pulse width, cardiac QRS slew rate, amplitude and stability measures of these parameters from the filtered cardiac signal information are measured, processed and integrated to determine if the cardioverter/defibrillator needs to initiate therapeutic action.

Claims

1. An implantable medical device (IMD) configured for monitoring a patient'"'"'s cardiac rhythm to determine whether an arrhythmia is occurring, the IMD comprising:

a housing containing a battery and operational circuitry for the IMD, the operational circuitry comprising an ECG input, an amplifier, one or more filter circuits, and a detector configured to detect QRS events; and

at least first and second electrodes on the housing and electrically coupled to the operational circuitry, the electrodes configured for sensing a cardiac signal of the patient;

wherein the operational circuitry is configured to detect one or more QRS signals for the patient during a normal sinus rhythm;

wherein the operational circuitry is further configured to detect atrial fibrillation (AF) by determining whether detected signals show an absence of P-waves between consecutive QRS signals by differentiating between a well-defined P-wave and a low-amplitude signal; and

wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a polarity relationship of the P-wave to the QRS.

2. The IMD of claim 1 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a rate of the P-wave.

3. The IMD of claim 1 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a morphology of the P-wave.

4. The IMD of claim 1 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including an amplitude of the P-wave.

5. The IMD of claim 1 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a frequency content of the P-wave.

6. The IMD of claim 1 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a timing relative to the QRS.

7. The IMD of claim 1 wherein the operational circuitry is further configured to detect AF by monitoring for stability of the coupling interval between R-waves in the QRS signal and finding irregularly spaced R-waves.

8. The IMD of claim 1 wherein the operational circuitry is further configured, in the event that AF is not identified, to determine whether a cardiac rate of the patient exceeds a threshold and, if so, to deliver defibrillation therapy to the patient.

9. The IMD of claim 1 wherein the operational circuitry is further configured, in the event that AF is identified, to deliver cardioversion therapy to the patient to terminate the detected AF, further wherein the operational circuitry is configured to deliver the cardioversion therapy by detecting the onset of the QRS signal and delivering the cardioversion shock during a synchronized time period.

10. An implantable medical device (IMD) configured for monitoring a patient'"'"'s cardiac rhythm to determine whether an arrhythmia is occurring, the IMD comprising:

a housing containing a battery and operational circuitry for the IMD, the operational circuitry comprising an ECG input, an amplifier, one or more filter circuits, and a detector configured to detect QRS events; and

at least a first electrode on the housing and electrically coupled to the operational circuitry, the first electrode configured for sensing a cardiac signal of the patient;

at least a second electrode disposed on an implantable lead configured for coupling to the housing to electrically couple the second electrode to the operational circuitry, the second electrode configured for sensing a cardiac signal of the patient;

wherein the operational circuitry is configured to detect one or more QRS signals for the patient during a normal sinus rhythm;

wherein the operational circuitry is further configured to detect atrial fibrillation (AF) by determining whether detected signals show an absence of P-waves between consecutive QRS signals by differentiating between a well-defined P-wave and a low-amplitude signal; and

wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a polarity relationship of the P-wave to the QRS.

11. The IMD of claim 10 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a rate of the P-wave.

12. The IMD of claim 10 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a morphology of the P-wave.

13. The IMD of claim 10 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including an amplitude of the P-wave.

14. The IMD of claim 10 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a frequency content of the P-wave.

15. The IMD of claim 10 wherein the operational circuitry is configured to establish one or more parameters for P-waves associated with QRS signals including a timing relative to the QRS.

16. The IMD claim 10 wherein the operational circuitry is further configured to detect AF by monitoring for stability of the coupling interval between R-waves in the QRS signal and finding irregularly spaced R-waves.

17. The IMD of claim 10 wherein the operational circuitry is further configured, in the event that AF is not identified, to determine whether a cardiac rate of the patient exceeds a threshold and, if so, to deliver defibrillation therapy to the patient.

18. The IMD of claim 10 wherein the operational circuitry is further configured, in the event that AF is identified, to deliver cardioversion therapy to the patient to terminate the detected AF, further wherein the operational circuitry is configured to deliver the cardioversion therapy by detecting the onset of the QRS signal and delivering the cardioversion shock during a synchronized time period.