Modified amino acids
First Claim
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1. A polypeptide which is a polymer of amino acid residues where one or more amino acid residues is according to the following formula IIc:
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Abstract
Provided herein are modified amino acids comprising an azido group, polypeptides, antibodies and conjugates comprising the modified amino acids, and methods of producing the polypeptides, antibodies and conjugates comprising the modified amino acids. The polypeptides, antibodies and conjugates are useful in methods of treatment and prevention, methods of detection and methods of diagnosis.
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15 Claims
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1. A polypeptide which is a polymer of amino acid residues where one or more amino acid residues is according to the following formula IIc:
- 2. A polypeptide which is a polymer of amino acid residues where one or more amino acid residues comprises the compound according to the following formula:
- 4. A conjugate prepared by contacting an alkyne-containing payload with a polypeptide which is a polymer of amino acid residues where one or more amino acid residues is according to formula IIa:
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8. A method for producing a conjugate, comprising:
a) combining an alkyne-containing carbohydrate, which optionally comprises a linker between the alkyne and the carbohydrate, with a polypeptide which is a polymer of amino acid residues where one or more amino acid residues is according to formula IIa; - View Dependent Claims (9, 10, 11, 12, 13, 14, 15)
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