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Antagonists of IL-6 to raise albumin and/or lower CRP

  • US 9,994,635 B2
  • Filed: 01/05/2016
  • Issued: 06/12/2018
  • Est. Priority Date: 11/25/2008
  • Status: Active Grant
First Claim
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1. A method of reducing serum C-reactive protein (“

  • CRP”

    ) level in a patient with an inflammatory condition wherein interleukin-6 (“

    IL-6”

    ) is elevated by administering an effective amount of an anti-IL-6 antibody comprising the variable heavy and light chain polypeptides of SEQ ID NO;

    657 and SEQ ID NO;

    709 respectively and the constant regions of SEQ ID NO;

    588 and 586 and monitoring the patient to assess the reduction in the patient'"'"'s serum CRP level.

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