Tissue removal devices, systems and methods

• US 9,999,710 B2
• Filed: 04/26/2013
• Issued: 06/19/2018
• Est. Priority Date: 01/07/2009
• Status: Active Grant

• Current Assignee: Liquet Technologies Incorporated
• Original Assignee: Med-Logics Incorporated
• Inventors: Ross, Rodney L., Dennewill, James, Hughes, Gregg, Nazarifar, Nader
• Primary Examiner(s): GILBERT, ANDREW M
• Application Number:
  US14/425,971
• Publication Number:
  US 20150306286A1
• Time in Patent Office: 1,880 Days
• CPC Class Codes: A61F 9/00745 using mechanical vibrations, e.g. ultrasonic
• CPC Class Codes: A61M 1/743 by changing the cross-section of the line, e.g. flow regulating valves A61M1/7413 takes precedence
• CPC Class Codes: A61M 1/75 Intermittent or pulsating suction A61M1/63, A61M1/772 take precedence
• CPC Class Codes: A61M 2210/0612 Eyes

Abstract

A tissue removal device includes a rigid aspiration cannula, a valve communicating with the aspiration cannula in a fluid-sealed manner, and a pneumatically-driven actuator configured for moving the valve between an open position and a closed position, wherein at the open position the valve defines an aspiration path through the aspiration cannula and the valve, and at the closed position the valve prevents vacuum from being applied at the distal tip.

Claims

1. A tissue removal device, comprising:

a housing;

a rigid aspiration cannula extending from the housing to a distal tip outside the housing, the distal tip having a distal opening;

a valve disposed in the housing, the valve comprising a valve port communicating with the aspiration cannula in a fluid-sealed manner; and

an aspiration line communicating with the valve and passing through the housing of the tissue removal device to provide a fluid connection between the aspiration cannula and a collection receptacle comprising an interior, an aspiration inlet communicating with the aspiration line and the interior, and a vacuum outlet communicating with the interior and configured for communication with a vacuum source, wherein the vacuum source creates a vacuum in a fluid circuit comprising the collection receptacle, the aspiration line, and the aspiration cannula, the valve being controlled to open and close to provide a pulsed vacuum;

a pneumatically-driven actuator configured for moving the valve between an open position and a closed position, wherein;

at the open position, the valve port is open wherein the valve defines an aspiration path through the aspiration cannula and the valve; and

at the closed position, the valve port is closed wherein the valve prevents vacuum from being applied at the distal tip,

wherein the valve comprises an inner cannula and an outer cannula coaxially disposed about at least a portion of the inner cannula, the inner cannula is configured for communicating with the vacuum source via the aspiration line and is linearly movable by the actuator between the open position and the closed position, the valve port is formed in the outer cannula, at the open position the aspiration path passes through the outer cannula via the valve port and into the inner cannula, and at the closed position the inner cannula blocks the valve port.

2. The tissue removal device of claim 1, where the collection receptacle comprises:

a cassette configured for being operated in an installed position at which the cassette is removably inserted into a console, and at the installed position the vacuum outlet communicates with the vacuum source, the cassette defining the interior of the collection receptacle,

wherein the aspiration path runs through the aspiration line and into the interior.

3. The tissue removal device of claim 2, wherein:

the cassette comprises a fluid-routing chamber, a collection chamber communicating with the vacuum outlet, an interior structure fluidly isolating the fluid-routing chamber from the collection chamber, and a cassette inlet leading from outside the cassette into the fluid-routing chamber;

the interior structure comprises a transfer passage between the fluid-routing chamber and the collection chamber;

the aspiration inlet communicates with the transfer passage; and

the aspiration line passes through the cassette inlet and into communication with the aspiration inlet, wherein the aspiration path runs through the transfer passage and into the collection chamber.

4. The tissue removal device of claim 1 further comprising:

an ultrasonic tip in the aspiration cannula, the ultrasonic tip connected to a phacoemulsification system.

5. The tissue removal device of claim 1 further comprising:

a soft membrane covering the distal tip and extending over at least a portion of the aspiration cannula, the soft membrane comprising an aspiration port positioned to provide a fluid path into the distal tip opening, the soft membrane composed of a flexible material.

6. The tissue removal device of claim 1, wherein the area of the valve port opening is greater than the area of the distal opening.

7. The tissue removal device of claim 1 where the valve in the housing is a first valve, the tissue removal device further comprising:

a second valve configured to open and close the aspiration line, the second valve positioned along the aspiration line between the housing and the aspiration inlet of the collection receptacle, where the second valve is controlled to either augment vacuum manipulation with the first valve or to provide a purging function to clear the aspiration line of obstructing tissue material.

8. The tissue removal device of claim 7 further comprising:

a third valve configured to open and close the aspiration line, the second valve positioned along the aspiration line between the housing and the aspiration inlet of the collection receptacle where the second valve is controlled to augment vacuum manipulation with the first valve and the third valve is controlled to provide a purging function to clear the aspiration line of obstructing tissue material.

9. The tissue removal device of claim 7 where the second valve comprises an anvil tip structure disposed to contact the aspiration line and coupled to a solenoid, wherein the solenoid is electrically controlled to move the anvil tip in one direction to pinch the aspiration line and in the opposite direction to open the aspiration line.

10. The tissue removal device of claim 7 where the second valve comprises a flat tip structure disposed to contact the aspiration line and coupled to a solenoid, wherein the solenoid is electrically controlled to move the flat tip in one direction to pinch the aspiration line and in the opposite direction to open the aspiration line.

11. The tissue removal device of claim 8 where:

the second valve comprises an anvil tip structure disposed to contact the aspiration line and coupled to a first solenoid, and

the third valve comprises a flat tip structure disposed to contact the aspiration line and coupled to a second solenoid.

12. The tissue removal device of claim 1 further comprising:

a control console comprising a processor for executing functions comprising programmed instructions for controlling the pulsed vacuum in the fluid circuit.

13. The tissue removal device of claim 12 where the control console is configured to provide a pulsed vacuum as a series of vacuum pulses having a vacuum on period followed by a vacuum off period to form a pulse period, the vacuum pulses being generated at a frequency determined by the pulse period.

14. The tissue removal device of claim 12 where the control console is configured to provide a pulsed vacuum as a series of vacuum pulses having a vacuum on period followed by a vacuum off period to form a pulse period, the vacuum pulses being generated with a duty cycle determined by adjusting the vacuum on period for a given pulse period.

15. The tissue removal device of claim 12 where the control console is configured:

to control an extent to which the valve port is open, and

to provide a pulsed vacuum as a series of vacuum pulses defined by a maximum vacuum level and a minimum vacuum level where the maximum vacuum level and the minimum vacuum level correspond to the extent to which the valve port is opened,

the maximum vacuum level corresponding to the valve port being up to 100% open, and

the minimum vacuum level corresponding to the valve port being closed or at least partially open.

16. The tissue removal device of claim 12 where the control console is configured to:

receive user input to determine a flow rate in the fluid circuit; and

control the flow rate based on the user input by controlling a base vacuum provided by a vacuum pump.

17. A tissue removal device, comprising:

a housing;

a rigid aspiration cannula extending from the housing to a distal tip outside the housing, the distal tip having a distal opening;

a first valve disposed in the housing, the first valve comprising a valve port communicating with the aspiration cannula in a fluid-sealed manner;

an aspiration line communicating with the first valve and passing through the housing of the tissue removal device to provide a fluid connection between the aspiration cannula and a collection receptacle comprising an interior, an aspiration inlet communicating with the aspiration line and the interior, and a vacuum outlet communicating with the interior and configured for communication with a vacuum source, wherein the vacuum source creates a vacuum in a fluid circuit comprising the collection receptacle, the aspiration line, and the aspiration cannula, the first valve being controlled to open and close to provide a pulsed vacuum;

a second valve configured to open and close the aspiration line, the second valve positioned along the aspiration line between the housing and the aspiration inlet of the collection receptacle, where the second valve is controlled to either augment vacuum manipulation with the first valve or to provide a purging function to clear the aspiration line of obstructing tissue material; and

a third valve configured to open and close the aspiration line, the second valve positioned along the aspiration line between the housing and the aspiration inlet of the collection receptacle where the second valve is controlled to augment vacuum manipulation with the first valve and the third valve is controlled to provide a purging function to clear the aspiration line of obstructing tissue material.