Pharmaceutical delivery system
First Claim
1. permeability of the coating dispersed therein..]. .[.6. The composition of claim 5 wherein the water permeability increasing agent is polyethylene
3 Assignments
0 Petitions
Accused Products
Abstract
A composition for use in an aqueous environment which .[.comprise.]. .Iadd.comprises .Iaddend.a formulation containing a water-soluble pharmaceutically beneficial agent, a water-insoluble, water-permeable film coating surrounding the formulation, and particulate, water-soluble, pore-forming material dispersed within the film coating.
The questions raised in reexamination request No. 90/001,344, filed Oct. 5, 1987, have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U.S.C. 307 as provided in 37 CFR 1.570(e).
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Citations
2 Claims
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1. permeability of the coating dispersed therein..]. .[.6. The composition of claim 5 wherein the water permeability increasing agent is polyethylene
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2. glycol..]. .Iadd.7. A controlled release composition for oral administration comprising bupropion hydrochloride in solid sustained release pharmaceutical carrier, said composition releasing about 10% to 45% of bupropion hydrochloride within two hours, releasing about 25% to 70% of bupropion hydrochloride within four hours, and releasing about 40% to 90% of bupropion hydrochloride within six hours, as measured in simulated gastric buffer with a pH of 1.5 at 37°
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Specification
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- Resources
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Current AssigneeSmithkline Beecham Corporation (GSK plc)
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Original AssigneeBurroughs Wellcome and Co.
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InventorsBaker, Richard W., Brooke, James W.
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Primary Examiner(s)Griffin, Ronald W.
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Application NumberUS07/390,518Time in Patent Office1,075 DaysField of Search424/465, 424/473, 424/468, 424/469, 514/964, 604/890, 604/892, 604/893US Class Current424/465CPC Class CodesA61K 31/135 having aromatic rings , e.g...A61K 9/2853 obtained otherwise than by ...
