Ophthalmic surgery method using non-contact scanning laser

• US RE37,504 E1
• Filed: 05/27/1998
• Issued: 01/08/2002
• Est. Priority Date: 12/03/1992
• Status: Expired due to Fees

• Current Assignee: Lasersight Technologies Inc. (Xianding Weng)
• Original Assignee: Lasersight Technologies Inc. (Xianding Weng)
• Inventors: Lin, J. T.
• Primary Examiner(s): PEFFLEY, MICHAEL F
• Application Number:
  US09/084,441
• Time in Patent Office: 1,322 Days
• Field of Search: 606/2-6, 606/10-12, 128/898
• US Class Current: 606/5
• CPC Class Codes: A61B 18/203 applying laser energy to the outside of the body
• CPC Class Codes: A61B 2018/20359 by movable mirrors, e.g. galvanometric
• CPC Class Codes: A61F 2009/00853 Laser thermal keratoplasty or radial keratotomy
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 2009/00882 based on topography
• CPC Class Codes: A61F 2009/00897 Scanning mechanisms or algorithms
• CPC Class Codes: A61F 9/008 using laser
• CPC Class Codes: A61F 9/00804 Refractive treatments
• CPC Class Codes: A61F 9/00821 for coagulation
• CPC Class Codes: B23K 2103/32 Material from living organisms, e.g. skins
• CPC Class Codes: B23K 2103/50 Inorganic material, e.g. metals, not provided for in B23K2103/02 – B23K2103/26
• CPC Class Codes: B23K 26/0622 by shaping pulses
• CPC Class Codes: B23K 26/361 for deburring or mechanical trimming B23K26/351 takes precedence

Abstract

A refractive laser surgery process is disclosed for using compact, low-cost ophthalmic laser systems which have computer-controlled scanning with a non-contact delivery device for both photo-ablation and photo-coagulation in corneal reshaping. The basic laser systems may include flash-lamp and diode pumped UV solid state lasers (193-215 nm), compact excimer laser (193 nm), free-running Er:glass (1.54 microns), Ho:YAG (2.1 microns), Q-switched Er:YAG (2.94 microns), and tunable IR lasers, (750-1100) nm and (2.5-3.2) microns. The advantages of the non-contact, scanning device used in the process over other prior art lasers include being safer, reduced cost, more compact and more precise and with greater flexibility. The theory of beam overlap and of ablation rate and coagulation patterns is also disclosed for system parameters. Lasers are selected with energy of (0.01-10) mJ, repetition rate of (1-10,000), pulse duration of 0.01 nanoseconds to a few hundreds of microseconds, and with spot size of (0.05-2) mm for use with refractive laser surgery.

Claims

1. A method of performing corneal refractive surgery by reshaping a portion of a corneal surface comprising the steps of:

selecting a laser having a pulsed output beam of predetermined ultraviolet wavelength and having an energy level less than of no greater than 10 mJ/pulse;

selecting a scanning mechanism for scanning said selected laser output beam, said scanning mechanism including a galvanometer scanning mechanism for controlling said laser beam into an overlapping pattern of adjacent pulses;

coupling said laser beam to a scanning device for scanning said laser beam over a predetermined surface;

focusing said scanning laser beam onto a corneal surface to a predetermined generally fixed spot size;

aligning the center of the said scanning laser beam onto the corneal surface with a visible aiming beam;

controlling the scanning mechanism to deliver the scanning laser beam in a predetermined overlapping pattern onto a plurality of positions on the corneal surface to photoablate or photocoagulate corneal tissue; and

removing from 0.05 to 0.5 microns of corneal tissue per pulse overlapped to remove tissue to a desired depth, whereby a patient'"'"'s vision is corrected by the reshaping of the corneal surface of the patient'"'"'s eye using a low power laser.

2. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting a diode-pumped UV laser having an output wavelength between 193 and 220 nanometers, and energy per pulse of 0.01 to 5 mJ/pulse, a repetition rate of between 1 Hz and 10 KHz, and a pulse duration between 0.1 picoseconds to 50 nanoseconds and a focused spot size of (0.05-1.5) mm on the corneal surface.

3. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting a flash lamp pumped UV laser having an output wavelength between 193 and 220 nanometers, and energy per pulse of 0.1 to 10 mJ/pulse, a repetition rate of between 1 Hz and 10 KHz, and a pulse duration between 0.1 picoseconds to 50 nanoseconds and a focused spot size of (0.05-1.5) mm on the corneal surface.

4. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting an argon fluoride excimer laser having an output wavelength of 193 nanometers, energy per pulse of 0.5 to 10 mJ/pulse and a focused generally fixed spot size of between 0.2 to 2 mm on the corneal surface, and a repetition rate of between 1 to 1,000 Hz, and pulse duration of between 1 to 50 nanoseconds.

5. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting a free-running Ho:

YAG laser having an output wavelength of about 2.1 microns at an average power of between 0.5-5 watts and a focused generally fixed spot size of between 0.1-1 mm.

6. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting a free-running Er:

glass laser having an output wavelength of about 1.54 microns at an average power of between 0.5-5 watts with a focused generally fixed spot size of between 0.1-1 mm.

7. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting a free-running Er:

glass laser having an output wavelength of between 1.9 to 2.5 microns at a power of between 0.5-5 watts and a focused generally fixed spot size of between 0.1-1 mm.

8. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting a Q-switched Er:

YAG laser having an output wavelength of 2.94 microns, and a pulse duration of between 50 to 400 nanoseconds, with an energy per pulse of between 50-500 mJ and a repetition rate of between 1 and 200 Hz with a focused generally fixed spot size of between 0.2-2 mm.

9. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting an ultra-short pulsed laser having an output wavelength of between 750 to 1100 nanometers, energy per pulse of between 0.01 to 100 microjoules, and a repetition rate of between 0.01 to 100 MHz, and pulse duration of between 0.05-10 picoseconds and a focused generally fixed spot size of between 0.05-0.5 mm.

10. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of selecting a laser includes selecting an OPO mid-IR laser having an output of 2.5-3.2 microns, a pulse duration of between 1-40 nanoseconds and energy per pulse of between 0.1 to 10 mJ, and a repetition rate of between 10 and 5,000 Hz and a focused generally fixed spot size on the corneal surface of between 0.1-2 mm.

11. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of delivering said laser beam includes said focusing lens which is highly transparent to the said laser beam, said focusing lens having a focal length of (50-1500) mm for focusing the laser source onto a generally fixed spot size of 0.05-2 mm on a predetermined position on the corneal surface.

12. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning mechanism includes controlling said scanning to scan a pattern of radial aligned spots using a laser beam capable of photocoagulation corneal tissue.

13. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning mechanism includes controlling said scanning to scan a pattern of concentric generally fixed spots using a laser beam capable of photocoagulating corneal tissue.

14. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning device includes controlling said scanning to scan a pattern of generally fixed area ring spots using a laser beam capable of photocoagulating corneal tissues.

15. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning device includes controlling said scanning to scan a pattern of overlapping generally fixed ring spots using a laser beam capable of photoablating corneal tissue for myopic correction.

16. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning mechanism includes controlling said scanning to scan a pattern of overlapping generally fixed area spots using a laser beam capable of photoablating the corneal tissue for hyperopic correction.

17. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning mechanism includes controlling said scanning to scan a pattern of overlapping circles of fixed area using a laser beam capable of photoablating the corneal tissue for astigmatic correction.

18. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning mechanism includes controlling said scanning to scan a pattern of radial aligned slits of fixed area using a laser beam capable of photoablating corneal tissue for laser radial keratectomy.

19. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 18 wherein the step of scanning includes scanning a coated window having a predetermined coating to direct said laser beam therethrough and to photoablate the corneal surface to meet a predetermined profile for refractive corrections.

20. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 18 in which the step of scanning includes scanning through a coated window made of materials transparent to a UV laser having an output beam of (193-215) nm.

21. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 18 in which the step of scanning includes scanning through a coated window made of materials highly transparent to an IR laser having an output beam of (2.5-3.2) microns.

22. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 in which the step of controlling said scanning mechanism includes controlling said scanning which has a circular scanning pattern to deliver uniform laser energy over a coated window positioning near the corneal surface.

23. A method of performing corneal refractive surgery by reshaping a portion of the corneal surface in accordance with claim 1 including the step of scanning in a uniform scanned pattern with a spatial overlap of 50-80% and beam orientation whereby the initial beam profile uniformity is not critical.

24. An ophthalmic surgery apparatus, comprising:

25. The ophthalmic surgery apparatus according to claim 24, wherein:

26. The ophthalmic surgery apparatus according to claim 24, wherein:

27. The ophthalmic surgery apparatus according to claim 24, wherein said scanning device comprises:

28. The ophthalmic surgery apparatus according to claim 24, wherein:

29. The ophthalmic surgery apparatus according to claim 24, wherein:

successive pulses of said pulsed beam are rotated through a linear-scan angle by said scanning device.

30. The ophthalmic surgery apparatus according to claim 24, wherein said optical device comprises:

31. The ophthalmic surgery apparatus according to claim 24, wherein said optical device comprises:

32. The ophthalmic surgery apparatus according to claim 24, wherein said optical device comprises:

33. A method for performing ophthalmic surgery comprising:

34. The method for performing ophthalmic surgery according to claim 33, wherein:

35. The method for performing ophthalmic surgery according to claim 34, wherein:

36. The method for performing ophthalmic surgery according to claim 33, wherein:

37. The method for performing ophthalmic surgery according to claim 33, wherein:

38. The method for performing ophthalmic surgery according to claim 33, wherein:

39. The method for performing ophthalmic surgery according to claim 33, wherein:

40. The method for performing ophthalmic surgery according to claim 33, wherein:

41. The method for performing ophthalmic surgery according to claim 33, wherein:

42. The method for performing ophthalmic surgery according to claim 33, wherein:

43. The method for performing ophthalmic surgery according to claim 33, wherein said scanning comprises:

44. The method for performing ophthalmic surgery according to claim 33, wherein said optical device comprises:

45. The method for performing ophthalmic surgery according to claim 33, wherein said optical device comprises:

46. The method for performing ophthalmic surgery according to claim 33, wherein said scanning comprises:

47. The method for performing ophthalmic surgery comprising:

48. The method for performing ophthalmic surgery according to claim 47, wherein:

49. The method for performing ophthalmic surgery according to claim 47, wherein:

50. The method for performing ophthalmic surgery according to claim 47, wherein:

51. The method for performing ophthalmic surgery according to claim 47, wherein:

52. The method for performing ophthalmic surgery according to claim 47, wherein:

53. The method for performing ophthalmic surgery according to claim 47, wherein:

54. A method of performing laser ablation on tissue, said method comprising:

55. The method of performing laser ablation on tissue according to claim 54, wherein:

56. The method of performing laser ablation on tissue according to claim 54, wherein:

57. The method of performing laser ablation on tissue according to claim 54, wherein:

58. The method of performing laser ablation on tissue according to claim 54, wherein:

59. The method of performing laser ablation on tissue according to claim 58, wherein:

60. The method of performing laser ablation on tissue according to claim 54, wherein:

61. The method of performing laser ablation on tissue according to claim 54, wherein:

62. The method of performing laser ablation on tissue according to claim 54, wherein:

63. The method of performing laser ablation on tissue according to claim 54, wherein:

64. The method of performing laser ablation on tissue according to claim 54, wherein:

65. The method of performing laser ablation on tissue according to claim 54, wherein:

66. The method of performing laser ablation on tissue according to claim 54, wherein:

67. The method of performing laser ablation on tissue according to claim 66, wherein:

68. A method for ablating tissue, comprising:

69. The method for ablating tissue according to claim 68, wherein:

70. The method for ablating tissue according to claim 68, wherein:

71. The method for ablating tissue according to claim 68, wherein:

72. The method for ablating tissue according to claim 68, wherein:

73. The method for ablating tissue according to claim 68, wherein:

74. The method for ablating tissue according to claim 68, wherein:

75. The method for ablating tissue according to claim 68, wherein said scanning comprises:

76. The method for ablating tissue according to claim 68, wherein said optical device comprises:

77. The method for ablating tissue according to claim 68, wherein said optical device comprises:

78. The method for ablating tissue according to claim 68, wherein said scanning comprises:

79. An ophthalmic surgery apparatus for performing corneal refractive surgery by reshaping a portion of a corneal surface, said apparatus comprising:

80. A method of performing corneal refractive surgery by reshaping a portion of corneal surface, said method comprising:

81. The method of performing corneal refractive surgery by reshaping a portion of a corneal surface according to claim 80, further comprising:

82. The method of performing corneal refractive surgery by reshaping a portion of a corneal surface according to claim 81, wherein:

83. A method for performing corneal refractive surgery by reshaping a portion of corneal surface, comprising:

84. The method for performing corneal refractive surgery according to claim 83, wherein said optical device comprises:

85. The method for performing corneal refractive surgery according to claim 83, further comprising:

86. A method for performing ophthalmic surgery, comprising:

87. The method of performing ophthalmic surgery according to claim 86, wherein:

88. The method of performing ophthalmic surgery according to claim 86, wherein:

89. The method for performing ophthalmic surgery according to claim 86, wherein:

90. The method of performing ophthalmic surgery according to claim 86, wherein:

91. The method of performing ophthalmic surgery according to claim 86, wherein: