Implantable pressure sensors and methods for making and using them

• US RE42,378 E1
• Filed: 07/20/2006
• Issued: 05/17/2011
• Est. Priority Date: 10/16/2000
• Status: Expired due to Term

• Current Assignee: Remon Medical Technologies Ltd. (Boston Scientific Corporation)
• Original Assignee: Remon Medical Technologies Ltd. (Boston Scientific Corporation)
• Inventors: Penner, Avi, Doron, Eyal, Ben-Yoseph, Alon, Wolinsky, Lone
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US11/491,533
• Time in Patent Office: 1,762 Days
• Field of Search: 607/32, 607/33, 607/60, 607/61, 600/300, 600/301
• US Class Current: 600/300
• CPC Class Codes: A61B 2560/0219 of externally powered implanted units
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 2562/028 Microscale sensors, e.g. electromechanical sensors [MEMS]
• CPC Class Codes: A61B 5/0028 Body tissue as transmission medium, i.e. transmission systems where the medium is the human body
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/031 Intracranial pressure
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61N 1/37217 characterised by the communication link, e.g. acoustic or tactile
• CPC Class Codes: A61N 1/3787 from an external energy source
• CPC Class Codes: A61N 2005/0651 Diodes
• CPC Class Codes: A61N 5/0601 Apparatus for use inside the body
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent

Abstract

An implant includes a pressure sensor, a controller for acquiring pressure data from the sensor, and an acoustic transducer for converting energy between electrical energy and acoustic energy. A capacitor is coupled to the acoustic transducer for storing electrical energy converted by the transducer and/or for providing electrical energy to operate the implant. The acoustic transducer may operate alternatively or simultaneously as an energy exchanger or an acoustic transmitter. During use, the implant is implanted within a patient'"'"'s body, and an external transducer transmits a first acoustic signal into the patient'"'"'s body, to energize the capacitor. The implant then obtains pressure data, and transmits a second acoustic signal to the external transducer, the second acoustic signal including the pressure data.

Claims

1. A surgical An implant, comprising:

a sensor for measuring intra-body diagnostic data;

a controller configured for generating that generates an electrical communication signal containing the measured diagnostic data;

one or more acoustic transducers;

circuitry for collectively configuring the one or more acoustic transducers to convert acoustic energy received from a location external to the implant into electrical energy used to support operation of the implant, and to convert the electrical communication signal received generated by the controller into an acoustical acoustic communication signal for transmission transmitted to a location external to the implant; and

an energy storage device configured for storing the electrical energy converted from acoustic energy by the one or more transducers, wherein the energy storage device comprises a first relatively fast-charging capacitor and a second relatively slow-charging capacitor, the first and second capacitors being coupled to the one or more acoustic transducers such that the first capacitor is charged first and the second capacitor is charged only upon substantially substantial charging of the first capacitor.

2. The implant of claim 1, wherein the one or more acoustic transducers are configured by the circuitry in a full-duplex mode, such that the one or more acoustic transducers can simultaneously convert the acoustic energy into electrical energy and convert the electrical communication signal into the acoustical communication acoustic communication comunication signal.

3. The implant of claim 2, wherein the one or more transducers comprise at least one receive only transducer for converting the acoustic energy into electrical energy, and at least one transmit only transducer for converting the electrical communication signal into the acoustical acoustic communication signal.

4. The implant of claim 2, wherein the one or more transducers comprises at least one transducer, each of which is configured by the circuitry for converting the acoustic energy into electrical energy, and at least one transducer configured for converting the electrical communication signal into the acoustic communication signal.

5. The implant of claim 1, wherein the one or more acoustic transducers are configured by the circuitry in a half-duplex mode, such that the one or more acoustic transducers can alternately convert the acoustic energy into electrical energy, and convert the electrical communication signal into the acoustic communication signal.

6. The implant of claim 1, wherein the one or more transducers are collectively configured by the circuitry for converting an acoustic communication signal transmitted from a location external to the implant to another electrical communication signal, the controller configured for detecting the other electrical communication signal.

7. The implant of claim 6, wherein the controller is configured for extracting one or more commands from the other electrical communication signal and controlling the implant in response to the one or more commands.

8. The implant of claim 7, wherein the controller is configured for activating or deactivating the energy storage device in response to the one or more commands.

9. The implant of claim 7, wherein the controller is configured for monitoring when the one or more acoustic transducers stop are converting acoustic energy into electrical energy, and for activating the implant when the transducers stop converting acoustic energy into electrical energy is no longer being converted by the one or more acoustic transducers.

10. The implant of claim 1, wherein the one or more acoustic transducers comprise:

each comprises a substrate comprising a cavity;

and a substantially flexible piezoelectric layer attached to the substrate across the cavity.

11. The implant of claim 10, each transducer further comprising a first electrode attached to an external surface of the piezoelectric layer and a second electrode attached to an internal surface of the piezoelectric layer.

12. The implant of claim 10, wherein the substrate of at least one transducer comprises an array of cavities, and wherein with the respective piezoelectric layer is bonded to the substrate over the array of cavities.

13. The implant of claim 10, wherein the piezoelectric layer comprises poly vinylidene fluoride.

14. The implant of claim 1, wherein the energy storage device is rechargeable.

15. The implant of claim 1, wherein the diagnostic data is pressure data.

16. The implant of claim 1, wherein the electrical energy is alternating current electrical energy, and wherein the controller circuitry is configured for converting alternating current electrical energy into direct current electrical energy for storage in the energy storage device.

17. The implant of claim 1, wherein the controller is configured to reset the implant when the energy storage device is being chargedby the electrical energy.

18. The implant of claim 1, wherein the controller is configured for automatically switching the implant off when the electrical energy available from the energy storage device falls below a predetermined threshold.

19. A surgical An implant, comprising:

a controller configured for controlling the operation of the implant;

and for generating an electrical communication signal;

one or more acoustic transducers;

circuitry for collectively configuring the one or more acoustic transducers to convert the electrical communication signal into an acoustical acoustic communication signal for transmission transmitted to a location external to the implant, and to convert acoustic energy received from a location external to the implant into electrical energy used to support operation of the implant; and

an energy storage device configured for storing the electrical energy converted from acoustic energy, wherein the energy storage device comprises a first, relatively fast-charging capacitor and a second, relatively slow-charging capacitor, the first and second capacitors being coupled to the one or more acoustic transducers such that the first capacitor is charged first and the second capacitor is charged only upon substantially substantial charging of the first capacitor.

20. The implant of claim 19, wherein the one or more acoustic transducers are configured by the circuitry in a full-duplex mode, such that the one or more acoustic transducers can simultaneously convert the acoustic energy into electrical energy and convert the electrical communication signal into the acoustical comunication signal.

21. The implant of claim 20, wherein the one or more transducers comprise at least one receive only transducer for converting the acoustic energy into electrical energy, and at least one transmit only transducer for converting the electrical communication signal into the acoustical communication signal.

22. The implant of claim 20, wherein the one or more transducers comprises at least one transducer, each of which is configured by the circuitry for converting the acoustic energy into electrical energy and for converting the electrical communication signal into the acoustic communication signal.

23. The implant of claim 19, wherein the one or more acoustic transducers are configured by the circuitry in a half-duplex mode, such that the one or more acoustic transducers can alternately convert the acoustic energy into electrical energy and convert the electrical communication signal into the acoustic communication signal.

24. The implant of claim 19, wherein the one or more transducers are collectively configured by the circuitry for converting an acoustic communication signal transmitted from a location external to the implant to another electrical communication signal, the controller configured for detecting the other electrical communication signal.

25. The implant of claim 24, wherein the controller is configured for extracting one or more commands from the other electrical communication signal and controlling the implant in response to the one or more commands.

26. The implant of claim 25, wherein the controller is configured for activating or deactivating the energy storage device in response to the one or more commands.

27. The implant of claim 25, wherein the controller is configured for monitoring when the one or more acoustic transducers stop converting electrical energy, and for activating the implant when electrical energy is no longer being converted by the one or more acoustic transducers.

28. The implant of claim 19, wherein the one or more acoustic transducers comprise:

each comprises a substrate comprising a cavity;

and a substantially flexible piezoelectric layer attached to the substrate across the cavity.

29. The implant of claim 28, further comprising a first electrode attached to an external surface of the piezoelectric layer and a second electrode attached to an internal surface of the piezoelectric layer.

30. The implant of claim 28, wherein the substrate of at least one transducer comprises an array of cavities, and wherein with the respective piezoelectric layer is bonded to the substrate over the array of cavities.

31. The implant of claim 28, wherein the piezoelectric layer comprises poly vinylidene fluoride.

32. The implant of claim 19, wherein the energy storage device is rechargeable.

33. The implant of claim 19, further comprising a sensor for acquiring diagnostic data, wherein the electrical communication signal generated by the transmission circuit contains the diagnostic data.

34. The implant of claim 19, wherein the electrical energy is alternating current electrical energy, and wherein the controller is configured for converting alternating current electrical energy into direct current electrical energy for storage in the energy storage device.

35. The implant of claim 19, wherein the controller is configured to reset the implant when the energy storage device is being charged by the electrical energy.

36. The implant of claim 19, wherein the controller is configured for automatically switching the implant off when the electrical energy available from the energy storage device falls below a predetermined threshold.

38. The implant of claim 19, wherein the one or more acoustic transducers are configured by the circuitry in a full-duplex mode, such that the one or more acoustic transducers can simultaneously convert the acoustic energy into electrical energy and convert the electrical communication signal into the acoustic communication signal.

39. The implant of claim 38, wherein the one or more transducers comprise at least one receive transducer for converting acoustic energy into electrical energy, and at least one transmit transducer for converting the electrical communication signal into the acoustic communication signal.

40. The implant of claim 38, wherein the one or more transducers comprises at least one transducer configured by the circuitry for converting acoustic energy into electrical energy, and at least one transducer for converting the electrical communication signal into the acoustic communication signal.

41. The implant of claim 19, wherein the one or more acoustic transducers are configured by the circuitry in a half-duplex mode, such that the one or more acoustic transducers can alternatively convert the acoustic energy into the electrical energy, and convert the electrical communication signal into the acoustic communication signal.

42. The implant of claim 19, wherein the one or more transducers are collectively configured by the circuitry for converting an acoustic communication signal transmitted from a location external to the implant to another electrical communication signal, the controller configured for detecting the other electrical communication signal.

43. The implant of claim 42, wherein the controller is configured for extracting one or more commands from the other electrical communication signal and controlling the implant in response to the one or more commands.

44. The implant of claim 42, wherein the controller is configured for activating or deactivating the energy storage device in response to the one or more commands.

45. The implant of claim 42, wherein the controller is configured for monitoring when the one or more acoustic transducers are converting acoustic energy into electrical energy, and for activating the implant when the transducers stop converting acoustic energy into electrical energy.

46. The implant of claim 28, each transducer further comprising a first electrode attached to an external surface of the piezoelectric layer and a second electrode attached to an internal surface of the piezoelectric layer.

47. The implant of claim 28, wherein the piezoelectric layer comprise poly vinylidene fluoride.

48. The implant of claim 19, wherein the energy storage device is rechargeable.

49. The implant of claim 19, further comprising a sensor for acquiring diagnostic data, wherein the electrical communication signal generated by the controller comprises the diagnostic data.

50. The implant of claim 19, wherein the electrical energy is alternating current electrical energy, and wherein the circuitry is configured for converting alternating current electrical energy into direct current electrical energy for storage in the energy storage device.

51. The implant of claim 19, wherein the controller is configured to reset the implant when the energy storage device is being charged.

52. The implant of claim 19, wherein the controller is configured for automatically switching the implant off when the electrical energy available from the energy storage device falls below a predetermined threshold.

37. An implant, comprising:

a sensor;

a controller that generates an electrical communication signal containing data measured by the sensor;

one or more acoustic transducers;

circuitry for collectively configuring the one or more acoustic transducers to convert acoustic energy received from a location external to the implant into electrical energy used to support operation of the implant, and to convert the electrical communication signal generated by the controller into an acoustic communication signal transmitted to a location external to the implant; and

an energy storage device configured for storing the electrical energy converted from acoustic energy by the one or more transducers, wherein the energy storage device comprises a first, relatively fast-charging capacitor and a second, relatively slow-charging capacitor, the first and second capacitors coupled to the one or more acoustic transducers such that the first capacitor is charged first and the second capacitor is charged only upon substantial charging of the first capacitor.