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Portable drug delivery device including a detachable and replaceable administration or dosing element

  • US RE46,217 E1
  • Filed: 02/05/2015
  • Issued: 11/29/2016
  • Est. Priority Date: 05/24/2005
  • Status: Active Grant
First Claim
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1. An apparatus for transdermally delivering a drug formulation and stopping dosing or delivery in an automatic, controllable manner, comprising:

  • (a) an active assembly comprising a controller;

    (b) a passive assembly adapted for mechanically coupling and decoupling with the active assembly, the passive assembly comprising;

    (i) a dispensing reservoir containing the drug formulation; and

    (ii) a delivery element comprising an administration reservoir and a membrane in fluid communication with the administration reservoir, the membrane being permeable to an active substance in the drug formulation;

    (c) a dispensing mechanism comprising;

    (i) an active portion in the active assembly providing a motive force to draw the drug formulation from the dispensing reservoir to the administration reservoir; and

    (ii) a passive portion in the passive assembly proximate to the active portion and defining a feed chamber through which the drug formulation flows from the dispensing reservoir; and

    (d) a stopping means for stopping dosing or slowing delivery by removing the drug or a solvent of the drug in the drug formulation from the administration reservoir, wherein the stopping means utilizes gas, air, fluid, or a combination thereof, which functions to flush the solvent, drug, or a combination thereof from the administration reservoir, and wherein the stopping means does not require removal of the apparatus from an application site during the flushing process.

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