Electrical ablation devices
First Claim
1. A method for using an electrical ablation apparatus, comprising:
- inserting an elongated tubular body made of an electrically conductive material comprising an arcuate closed distal end and a first electrode received in an open proximal end of the elongated tubular body into a first natural orifice of a body, wherein the first electrode is electrically coupled to the elongated tubular body;
inserting a second electrode, located external to the elongated tubular body, into the body;
electrically contacting a first conductive terminal of an energy source with the first electrode, and electrically contacting a second conductive terminal of the energy source with the second electrode; and
delivering, by the energy source, a first series of electrical pulses sufficient to induce cell necrosis by irreversible electroporation across the first electrode and the second electrode,wherein the first series of electrical pulses are characterized by a first amplitude, a first pulse length, and a first frequency.
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Accused Products
Abstract
An electrical ablation apparatus comprises first and second electrodes. Each electrode comprises a first end configured to couple an energy source and a second end configured to couple to a tissue treatment region. An energy source is coupled to the first and second electrodes. The energy source is configured to deliver a first series of electrical pulses sufficient to induce cell necrosis by irreversible electroporation and a second series of electrical pulses sufficient to induce cell necrosis by thermal heating, through at least one of the first and second electrodes. The first series of electrical pulses is characterized by a first amplitude, a first pulse length, and a first frequency. The second series of electrical pulses is characterized by a second amplitude, a second pulse length, and a second frequency.
1822 Citations
13 Claims
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1. A method for using an electrical ablation apparatus, comprising:
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inserting an elongated tubular body made of an electrically conductive material comprising an arcuate closed distal end and a first electrode received in an open proximal end of the elongated tubular body into a first natural orifice of a body, wherein the first electrode is electrically coupled to the elongated tubular body; inserting a second electrode, located external to the elongated tubular body, into the body; electrically contacting a first conductive terminal of an energy source with the first electrode, and electrically contacting a second conductive terminal of the energy source with the second electrode; and delivering, by the energy source, a first series of electrical pulses sufficient to induce cell necrosis by irreversible electroporation across the first electrode and the second electrode, wherein the first series of electrical pulses are characterized by a first amplitude, a first pulse length, and a first frequency. - View Dependent Claims (2, 3, 4, 5)
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6. An electrical ablation system, comprising:
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an elongated tubular body made of an electrically conductive material, the elongated tubular body comprising; an arcuate closed distal end configured for entry into a first natural orifice of a body; an open proximal end; and a first electrode received in the open proximal end of the elongated tubular body, the first electrode electrically coupled to the elongated tubular body; a visualization device configured to visualize an internal compartment of the body and configured to receive the elongated tubular body; a second electrode, located external to the elongated tubular body, the second electrode configured for entry into the body; and an energy source having a first conductive terminal in electrical communication with the first electrode and a second conductive terminal in electrical communication with the second electrode, the energy source configured to deliver a first series of electrical pulses sufficient to induce cell necrosis by irreversible electroporation across the first electrode and the second electrode; wherein the first series of electrical pulses are characterized by a first amplitude, a first pulse length, and a first frequency. - View Dependent Claims (7, 8, 9, 10, 11, 12, 13)
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Specification