Analyte sensor

  • US 10,022,078 B2
  • Filed: 05/23/2006
  • Issued: 07/17/2018
  • Est. Priority Date: 07/13/2004
  • Status: Active Grant
First Claim
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1. An analyte sensing device adapted for insertion into a host'"'"'s soft tissue, comprising:

  • a transcutaneous sensor comprising an in vivo portion and an ex vivo portion, wherein the sensor is configured to detect an analyte in the host, wherein the sensor comprises;

    a first electrode comprising an electroactive portion;

    a second electrode;

    a sensing membrane deposited on the electroactive portion, the sensing membrane comprising;

    a first domain comprising an enzyme configured to catalyze a reaction with the analyte; and

    a second domain comprising a carrier matrix storing a bioactive agent, wherein the second domain is configured to provide an interface with an in vivo environment, wherein the bioactive agent is configured to be released from the carrier matrix through a first release and through a second release to modify tissue response of the host, wherein the first release is configured to begin at a time associated with sensor insertion and end prior to end of sensor life, wherein the second release continues until end of sensor life, wherein the bioactive agent comprises dexamethasone; and

    a housing that houses sensor electronics configured for operable connection to sensor, wherein the sensor electronics is configured to process sensor data, and wherein the housing further comprises an adhesive pad for adhering the housing to the skin of the host.

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