Mobile smart device infrared light measuring apparatus, method, and system for analyzing substances

• US 10,031,076 B2
• Filed: 10/07/2015
• Issued: 07/24/2018
• Est. Priority Date: 06/28/2012
• Status: Active Grant

• Current Assignee: Quick, LLC
• Original Assignee: Quick, LLC
• Inventors: Mucci, David Anthony, Clark, Jr., Ronald Gary, Fox, James Scott
• Primary Examiner(s): Kim, Christine S
• Application Number:
  US14/877,157
• Publication Number:
  US 20160025624A1
• Time in Patent Office: 1,021 Days
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: G01J 3/0272 Handheld
• CPC Class Codes: G01N 21/03 Cuvette constructions
• CPC Class Codes: G01N 21/3577 for analysing liquids, e.g. polluted water
• CPC Class Codes: G01N 21/359 using near infrared light

Abstract

A handheld infrared spectroscopy device and method of use. The device is a hand-held spectroscopy device, that may be integral to a mobile phone or smart device such as a smart phone, tablet, personal digital assistant, computer or other device that is portable and capable of performing applications. A liquid sample port internal to the device and in close proximity to the device spectrometer performs infrared spectra analysis on liquid samples, allowing both portability as well as highly sophisticated and specific spectral analysis of liquid samples. The device has wireless communication capability, enabling transmission of data and spectral imagery across the globe.

Claims

1. A handheld spectroscopy device comprising:

an infrared light source that emits a first wavelength of light in the infrared range;

an infrared calibration emitter that emits a second wavelength of light, wherein the second wavelength is one or more of the same wavelength as the first wavelength and a different wavelength from the first wavelength of light emitted by the infrared light source;

a liquid sample test port and sample tray for receiving a liquid sample, the liquid sample test port and sample tray in close association with the infrared light source, wherein the infrared light emitted by the infrared light source and the infrared calibration emitter is directed through all or part of the sample on the sample tray, and wherein the sample tray is configured to allow the first and second wavelengths of light to pass therethrough and does not react with the liquid sample;

an infrared receiver for detecting the first wavelength of light emitted by the infrared light source and recording a spectrum of frequencies of infrared light absorption by the liquid sample, thereby obtaining a sample spectrum;

an infrared calibration receiver for detecting the second wavelength of light emitted by the infrared calibration emitter and recording a spectrum of frequencies of infrared light absorption, thereby obtaining a calibration spectrum; and

a data processor connected to the infrared receiver and the infrared calibration receiver to detect and quantify a concentration of one or more compounds in the liquid sample in the form of spectral data and/or an image using the recorded sample spectrum of frequencies and the recorded wavelength emitted by the infrared calibration emitter, wherein the concentration is quantified by comparing the sample spectrum to the calibration spectrum.

2. The device of claim 1, wherein the second wavelength is different from the first wavelength of light emitted by the infrared light source, and wherein the infrared range has a wavelength range of about 650 nm to about 15000 nm.

3. The device of claim 1 wherein the infrared range has a mid-IR wavelength range of about 3000 nm to about 15000 nm.

4. The device of claim 1 further comprising one or more infrared filters in close proximity to the infrared source, receiver, or both.

5. The device of claim 1 wherein the handheld device is a wireless communication device.

6. The device of claim 1, wherein the infrared light source and the infrared receiver are positioned on opposite sides of the sample tray, wherein the infrared calibration emitter is positioned at a same side with the infrared light source with respect to the sample tray, and the infrared calibration receiver is positioned at a same side with the infrared receiver with respect to the sample tray.

7. The device of claim 6 further comprising one or more infrared calibration filters in close proximity to the calibration infrared emitter, the calibration infrared receiver, or both.

8. The device of claim 1 wherein the sample tray is detachable from the device.

9. The device of claim 1 further comprising a data transmitter for transmitting the spectral data and/or image to a computer, handheld device, smart device, or other means of receiving the spectral data and/or image.

10. The device of claim 1 wherein the liquid sample comprises a bodily fluid.

11. A method for determining a concentration of one or more compounds in a bodily fluid using infrared spectroscopy, comprising:

placing a sample of the bodily fluid on a sample tray configured to allow infrared light having a first wavelength and a second wavelength to pass therethrough and does not react with the sample,

inserting the sample tray into a sample test port housed in a handheld device containing an infrared spectrometer, the infrared spectrometer including;

an infrared light source and an infrared receiver positioned at opposite sides of the sample tray, the infrared light source being configured to emit the first wavelength of light in the infrared range,

an infrared calibration emitter and an infrared calibration receiver positioned at opposite sides of the sample tray, the infrared calibration emitter being configured to emit the second wavelength of light, wherein the second wavelength of light is different from the first wavelength of light emitted by the infrared light source;

directing infrared light from the infrared light source and the infrared calibration emitter at the sample;

detecting, with the infrared receiver, wavelengths of infrared light emitted by the infrared light source as result of infrared light absorbed by the sample;

detecting, with the infrared calibration receiver, wavelengths of infrared light emitted by the infrared calibration receiver;

recording a sample spectrum of frequencies of infrared light absorption by the sample detected using the infrared receiver;

recording, a calibration spectrum of frequencies of infrared light detected using the infrared calibration receiver;

quantifying, with a processor of the infrared spectrometer, a concentration of one or more compounds in the sample by comparing the sample spectrum having the first wavelength of light to the calibration spectrum having the second wavelength of light; and

transmitting one or more of the concentration and the first and second spectrums of the frequencies of infrared light absorption by the sample via wireless communication network from the handheld device to one or more other devices.

12. The method of claim 11 wherein the bodily fluid is blood, urine, or saliva.

13. The method of claim 11 wherein the directed infrared light has a wavelength range of at least one of about 650 nm to about 3000 nm, about 650 nm to about 15000 nm, and about 3000 nm to about 15000 nm.

14. The method of claim 11 further comprising calibrating the handheld device.

15. The method of claim 11 further comprising displaying the presence or concentration of the one or more compounds as spectral data and/or imagery on the handheld device.

16. The method of claim 11 further comprising transmitting the presence or concentration of the one or more compounds via wireless communication network to one or more other devices.

17. A method of testing a liquid sample using infrared spectroscopy to detect or quantify one or more substances in the liquid sample, said method comprising:

receiving a liquid sample in a liquid test tray, wherein the liquid test tray is configured to allow infrared light to pass therethrough and does not react with the liquid sample, and wherein the liquid test tray is slideably connected to a port of a handheld spectroscopy device, the handheld spectroscopy device including;

an infrared light source and an infrared receiver positioned at opposite sides of the sample tray, the infrared light source being configured to emit a first wavelength of light in the infrared range, and

an infrared calibration emitter and an infrared calibration receiver positioned at opposite sides of the sample tray, the infrared calibration emitter being configured to emit a second wavelength of light different from the first wavelength of light emitted by the infrared light source;

exposing the liquid sample to infrared light emitted from the infrared emitter and infrared light emitted from the calibration emitter;

recording a first spectrum of frequencies of infrared light absorption by the infrared receiver and a second spectrum of frequencies of infrared light absorption by the infrared calibration receiver, thereby obtaining spectral data associated with the liquid sample;

quantifying, with a processor of the handheld spectroscopy device, a concentration of one or more compounds in the sample by comparing the first spectrum to the second spectrum; and

transmitting one or more of the concentration and the spectral data via wireless communication network from the handheld device to one or more other devices.

18. The method of claim 17 wherein the liquid sample is a sample of a bodily fluid.

19. The method of claim 17 wherein the liquid sample is an environmental fluid.

20. The method of claim 17 wherein the directed infrared light has a wavelength range of at least one of about 650 nm to about 3000 nm, about 650 nm to about 15000 nm, and about 3000 nm to about 15000 nm.