Automatic isothermal titration microcalorimeter apparatus and method of use

  • US 10,036,715 B2
  • Filed: 06/24/2016
  • Issued: 07/31/2018
  • Est. Priority Date: 12/02/2008
  • Status: Active Grant
First Claim
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1. An isothermal titration micro calorimetry (ITC) system, comprising;

  • a microcalorimeter,a pipette assembly comprising a syringe with a fill port configured to provide fluidic contact with a cavity of the syringe and an activator configured to drive a plunger in the cavity of the syringe,a rotatable pipette translation unit configured to place the pipette assembly in a titration position and in a washing position,a rotatable cell preparation unit configured to wash a sample cell of the microcalorimeter and replace sample liquid in the sample cell when the pipette assembly is placed in another position than the position for titration, anda fill port connection unit comprising a connection member configured to connect to the fill port thereby enabling fluid to transfer into the cavity of the syringe.

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