System and method for variable depth ultrasound treatment

• US 10,039,938 B2
• Filed: 04/29/2014
• Issued: 08/07/2018
• Est. Priority Date: 09/16/2004
• Status: Active Grant

• Current Assignee: Guided Therapy Systems Llc
• Original Assignee: Guided Therapy Systems Llc
• Inventors: Barthe, Peter G., Slayton, Michael H.
• Primary Examiner(s): Roy, Baisakhi
• Application Number:
  US14/264,732
• Publication Number:
  US 20140236049A1
• Time in Patent Office: 1,561 Days
• CPC Class Codes: A61B 2017/22024 with a part reflecting mechanical vibrations, e.g. for focusing
• CPC Class Codes: A61B 2017/22028 arrays, e.g. phased arrays
• CPC Class Codes: A61B 34/30 Surgical robots
• CPC Class Codes: A61N 2007/0065 Concave transducers
• CPC Class Codes: A61N 2007/0069 Reflectors
• CPC Class Codes: A61N 2007/0073 using multiple frequencies
• CPC Class Codes: A61N 2007/0095 by modifying an excitation signal
• CPC Class Codes: A61N 7/00 Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092

Abstract

A non-invasive variable depth ultrasound treatment method and system comprises a variable depth transducer system configured for providing ultrasound treatment to a patient. An exemplary variable depth transducer system can comprise a transducer configured to provide treatment to more than one region of interest, such as between a deep treatment region of interest and a superficial region of interest, and/or a subcutaneous region of interest. The variable depth transducer can comprise a transduction element having a piezoelectrically active layer, matching layers and/or other materials for generating radiation or acoustical energy. The variable depth transducer may be configured to operate at moderate frequencies within the range from approximately 750 kHz to 20 MHz or more. In addition, the transduction element may be configured with a variable depth device comprising one or more materials configured to allow for control and focusing/defocusing of the acoustic energy to more than one region of interest.

Claims

1. A non-invasive ultrasound treatment system for providing treatment to a patient, the system comprising:

a variable depth transducer system comprising;

a transducer having a surface and comprising at least one transduction element, and a variable depth element comprising a reflective surface, wherein;

the variable depth transducer system operable to provide treatment to a region of interest between a superficial and subcutaneous region of a patient, and

the reflective surface is configured to be inclined at any angle with respect to the transducer such that energy emitted by the surface of the transducer is bent, redirected or reflected from the reflective surface towards the region of interest;

wherein the variable depth transducer comprises a spatial control operable to change the angle of inclination of the reflective surface to focus the energy emitted by the surface of the transducer to any depth in the region of interest; and

a controller in communication with the transducer and the variable depth element, the controller comprising a control of the spatial control and a control of a frequency of the energy.

2. A non-invasive ultrasound treatment system for providing treatment to a patient, the system comprising:

a variable depth transducer system comprising;

a transducer having a surface and comprising at least one transduction element; and

a variable depth element comprising a reflective surface and a spatial control, the reflective surface configured to be inclined at an angle with respect to the transducer such that energy emitted by the surface of the transducer is bent, redirected or reflected from the reflective surface towards the region of interest, the spatial control configured to adjust the angle; and

a controller in communication with the transducer and the variable depth element, the controller configured to direct the spatial control to change the angle of inclination of the reflective surface to direct the energy emitted from the surface of the transducer to a pre-determined depth in the region of interest and to adjust a frequency of the energy.

3. The non-invasive ultrasound treatment system according to claim 2, wherein the variable depth transducer is configured for variable control of the energy to change a depth location for a lesion created with the region of interest.

4. The non-invasive ultrasound treatment system according to claim 2 further comprising a coupling system configured for acoustic coupling between the variable depth transducer system and the region of interest.

5. The non-invasive ultrasound treatment system according to claim 4 wherein the coupling system is configured fix temperature control of the transducer to facilitate adjustment of a focal depth of the energy emitted by the surface of the transducer.

6. The non-invasive ultrasound treatment system according to claim 2, further comprising a mechanical scanning device configured to move the variable depth transducer system in at least one of a translational movement and a rotational movement.

7. The non-invasive ultrasound treatment system according to claim 2 wherein the variable depth transducer system is configured to image the region of interest.

8. The non-invasive ultrasound treatment system according to claim 2, wherein the frequency of the energy is in a range of 750 kHz to 20 MHz.

9. The non-invasive ultrasound treatment system according to claim 2, wherein the frequency of the energy is in a range of 750 kHz to 8 MHz or a range of 8 MHz to 20 MHz.

10. The non-invasive ultrasound treatment system according to claim 2, wherein the transducer is coupled to the variable depth element and is configured to focus the energy emitted by the surface of the transducer to any depth in more than one region of interest.

11. The non-invasive ultrasound treatment system according to claim 2, wherein the reflective surface comprises at least one mirror.

12. The non-invasive ultrasound treatment system according to claim 11, wherein the mirror is substantially flat in shape.

13. The non-invasive ultrasound treatment system according to claim 11, wherein the mirror is curved in shape.

14. The non-invasive ultrasound treatment system according to claim 2, wherein the transducer is configured with spatial control to change at least one of a distance from the transducer to the reflective surface, and an angle of the energy delivered into the region of interest.

15. The non-invasive ultrasound treatment system according to claim 2, wherein the transducer is configured in a curved manner.

16. The non-invasive ultrasound treatment system according to claim 2, wherein the at least one transduction element is a plurality of transduction elements configured to be activated by a plurality of frequencies separated by at least one phase delay.

17. The non-invasive ultrasound treatment system according to claim 2, wherein the controller further comprises a display unit for displaying at least one of imaging information, positional information and temperature information of a treatment region.

18. The non-invasive ultrasound treatment system according to claim 2, wherein the controller further comprises a robotic arm arrangement for controlling movement of the variable depth.

19. The non-invasive ultrasound treatment system according to claim 18, wherein the controller movement of the variable depth transducer system is configured to create a plurality of lesions at varying depths in the region of interest.

20. The non-invasive ultrasound treatment system according to claim 2, wherein the energy is focused to a first depth in the superficial region and the energy is focused to a second depth in the subcutaneous region, wherein the first depth and the second depth is in a range from 0 mm to 5 cm, and the first depth is less than the second depth.