Preparation and uses of obeticholic acid

  • US 10,047,117 B2
  • Filed: 11/20/2015
  • Issued: 08/14/2018
  • Est. Priority Date: 06/19/2012
  • Status: Active Grant
First Claim
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1. A method of treating an FXR mediated disease or condition in a subject comprising administering to the subject a pharmaceutical formulation comprising an effective amount of a substantially pure solid form of obeticholic acid, wherein the solid form of obeticholic acid comprises less than 1% of chenodeoxycholic acid, and wherein the formulation comprises about 1 mg to about 30 mg of obeticholic acid.

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