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Methods of preventing progression to type 2 diabetes mellitus

  • US 10,058,532 B2
  • Filed: 06/30/2017
  • Issued: 08/28/2018
  • Est. Priority Date: 10/08/2013
  • Status: Active Grant
First Claim
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1. A method of delaying the progression from prediabetes to diabetes in a patient, comprising:

  • (a) identifying a patient at risk for developing type 2 comprising determining that the patient has at least one of the following;

    (i) HbA1c levels that are between 5.7% and 6.4%;

    (ii) plasma glucose levels between 7.8 mmol/L and 11 mmol/L; and

    (iii) blood glucose levels less between 6.1 mmol/L and 7.0 mmol/L; and

    (b) administering to the patient an oral dosage form comprising immediate release phentermine and controlled release topiramate.

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