Methods of preventing progression to type 2 diabetes mellitus
First Claim
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1. A method of delaying the progression from prediabetes to diabetes in a patient, comprising:
- (a) identifying a patient at risk for developing type 2 comprising determining that the patient has at least one of the following;
(i) HbA1c levels that are between 5.7% and 6.4%;
(ii) plasma glucose levels between 7.8 mmol/L and 11 mmol/L; and
(iii) blood glucose levels less between 6.1 mmol/L and 7.0 mmol/L; and
(b) administering to the patient an oral dosage form comprising immediate release phentermine and controlled release topiramate.
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Abstract
The present invention provides compositions and methods for delaying or preventing progression to type 2 diabetes mellitus in individuals with prediabetes and metabolic syndrome.
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16 Claims
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1. A method of delaying the progression from prediabetes to diabetes in a patient, comprising:
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(a) identifying a patient at risk for developing type 2 comprising determining that the patient has at least one of the following; (i) HbA1c levels that are between 5.7% and 6.4%; (ii) plasma glucose levels between 7.8 mmol/L and 11 mmol/L; and (iii) blood glucose levels less between 6.1 mmol/L and 7.0 mmol/L; and (b) administering to the patient an oral dosage form comprising immediate release phentermine and controlled release topiramate. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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Specification