Controlled release and taste masking oral pharmaceutical compositions
DC CAFCFirst Claim
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1. A controlled release oral pharmaceutical composition consisting essentially of:
- (1) a tablet core consisting of a matrix comprising;
a) budesonide in an amount to treat intestinal inflammation;
b) magnesium stearate, stearic acid, or a mixture thereof;
c) hydroxyalkyl cellulose; and
d) optionally starch or a starch derivative; and
(2) a coating on said tablet core, said coating consisting essentially of a gastro-resistant film.
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Abstract
The invention relates to tablet comprising granules dispersed in at least one hydrophilic compound or matrix. The granules contain an active agent, at least one amphiphilic compound and at least one lipophilic compound. The tablet may include a gastro-resistant film coating.
69 Citations
21 Claims
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1. A controlled release oral pharmaceutical composition consisting essentially of:
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(1) a tablet core consisting of a matrix comprising; a) budesonide in an amount to treat intestinal inflammation; b) magnesium stearate, stearic acid, or a mixture thereof; c) hydroxyalkyl cellulose; and d) optionally starch or a starch derivative; and (2) a coating on said tablet core, said coating consisting essentially of a gastro-resistant film. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification