Immunogenic composition

  • US 10,166,287 B2
  • Filed: 08/30/2017
  • Issued: 01/01/2019
  • Est. Priority Date: 06/27/2005
  • Status: Active Grant
First Claim
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1. An immunogenic composition, comprising N. meningitidis capsular polysaccharides from serogroups A, C, W, and Y, wherein:

  • the serogroup A capsular polysaccharide has an average size of 300 kDa;

    the serogroup C capsular polysaccharide has an average size of 200 kDa;

    the serogroup Y capsular polysaccharide has an average size of 101-300 kDa;

    the serogroup W capsular polysaccharide has an average size of 101-300 kDa; and

    wherein each N. meningitidis capsular polysaccharide is a N. meningitidis capsular polysaccharide conjugate comprising a N. meningitidis capsular polysaccharide conjugated to a tetanus toxoid carrier protein.

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