Infusion system which utilizes one or more sensors and additional information to make an air determination regarding the infusion system

• US 10,166,328 B2
• Filed: 05/29/2014
• Issued: 01/01/2019
• Est. Priority Date: 05/29/2013
• Status: Active Grant

• Current Assignee: ICU Medical Incorporated
• Original Assignee: ICU Medical Incorporated
• Inventors: Oruklu, Meriyan, Ruchti, Timothy L., Kotnik, Paul T., Belkin, Anatoly S.
• Primary Examiner(s): Zhang, Jenna
• Application Number:
  US14/289,848
• Publication Number:
  US 20140358077A1
• Time in Patent Office: 1,678 Days
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/1684 by detecting the amount of infusate remaining, e.g. signalling end of infusion
• CPC Class Codes: A61M 5/365 Air detectors A61M5/1684 takes precedence; in extracorporeal blood circuits A61M1/3626

Abstract

In one step of a method for infusing an infusion fluid, the infusion fluid is pumped through a fluid delivery line of an infusion system. In another step, measurements are taken with at least one sensor connected to the infusion system. In an additional step, an air determination is determined with at least one processor. The air determination is related to air in the fluid delivery line. The air determination is based on the measurements taken by the at least one sensor. The air determination is further based on: (1) medication information regarding the infusion fluid or infusion information regarding the infusion of the infusion fluid; or (2) multi-channel filtering of the measurements from the at least one sensor or non-linear mapping of the measurements from the at least one sensor; and statistical process control charts applied to the multi-channel filtered measurements or applied to the non-linear mapped measurements.

Claims

1. An infusion system configured to be connected to a fluid delivery line and to an infusion container containing an infusion fluid, the infusion system comprising:

a pump for pumping infusion fluid from the infusion container;

at least one force sensor connected to the pump or the fluid delivery line, the at least one force sensor configured to measure force on a plunger of the pump;

at least one processor in electronic communication with the pump and the at least one force sensor;

a memory in electronic communication with the at least one processor, the memory comprising programming code for execution by the at least one processor; and

wherein the programming code is configured to cause the at least one processor to;

estimate future derived force measurement based on an application of a Kalman filter on the measured force on the plunger, wherein the estimation of future derived force measurement comprises at least one of;

determine a mean force measurement based on the measured force;

determine a variance force measurement based on the measured force; and

determine a derivative force measurement based on the measured force;

calculate a residual between the future derived force measurement and the measured force;

construct a cumulative sum control chart based on the calculated residual; and

determine air in the fluid delivery line based on the cumulative sum control chart and volume of infusion fluid pumped from the infusion container.

2. An infusion method comprising:

pumping infusion fluid from an infusion container to a fluid delivery line;

measuring force on a plunger from a force sensor connected to a pump comprising the plunger or the fluid delivery line;

estimating future derived force measurements based on an application of a Kalman filter on the measured force on the plunger, wherein the estimation of the future derived force measurement comprises at least one of;

determining a mean force measurement based on the measured force;

determining a variance force measurement based on the measured force; and

determining a derivative force measurement based on the measured force;

calculating a residual between the future derived force measurement and the measured force;

constructing a cumulative sum control chart based on the calculated residual; and

determining air in the fluid delivery line based on the cumulative sum control chart and volume of infusion fluid pumped from the infusion container.