Method and device for assessment of a series of glucose concentration values of a body fluid of a diabetic for adjustment of insulin dosing
First Claim
Patent Images
1. A method for determining a disturbance parameter characterizing a disturbance of a tested glucose metabolism that is manifest despite the administration of insulin to adjust dosing of insulin administration, the method comprising:
- relating glucose concentration values g(t1) to g(tn) to time points t1 to tn that are distributed over a period of time of at least four hours;
using the glucose concentration values g(t1) to g(tn) as input parameters to a processor to calculate disturbance values w(g(t1)) to w(g(tn)) as function values of a weight function w, wherein the weight function w has a lesser slope in a target range of the glucose concentration values g(t1) to g(tn) than in a range that is adjacent to the target range;
determining the disturbance parameter on a processor from the disturbance values, wherein the disturbance parameter characterizes a type and/or severity of a disturbance of the tested glucose metabolism that is manifest despite the administration of insulin;
assigning the disturbance parameter on a processor by use of predetermined parameter ranges to one of at least two predetermined classes, wherein with each of the classes corresponding to recommendations for adjustment of the dosing of the insulin administrations are generated as output parameters;
signaling an output unit to output a recommendation for adjustment of the dosing of the insulin administrations corresponding to the assigned class; and
controlling an insulin administration device to adjust the dosing of the insulin administration in response to the recommendation.
3 Assignments
0 Petitions
Accused Products
Abstract
The invention relates to a method for assessment of a series of glucose concentration values of a body fluid of a diabetic for adjustment of the dosing of insulin administrations as well as a suitable device for carrying out the method.
-
Citations
19 Claims
-
1. A method for determining a disturbance parameter characterizing a disturbance of a tested glucose metabolism that is manifest despite the administration of insulin to adjust dosing of insulin administration, the method comprising:
-
relating glucose concentration values g(t1) to g(tn) to time points t1 to tn that are distributed over a period of time of at least four hours; using the glucose concentration values g(t1) to g(tn) as input parameters to a processor to calculate disturbance values w(g(t1)) to w(g(tn)) as function values of a weight function w, wherein the weight function w has a lesser slope in a target range of the glucose concentration values g(t1) to g(tn) than in a range that is adjacent to the target range; determining the disturbance parameter on a processor from the disturbance values, wherein the disturbance parameter characterizes a type and/or severity of a disturbance of the tested glucose metabolism that is manifest despite the administration of insulin; assigning the disturbance parameter on a processor by use of predetermined parameter ranges to one of at least two predetermined classes, wherein with each of the classes corresponding to recommendations for adjustment of the dosing of the insulin administrations are generated as output parameters; signaling an output unit to output a recommendation for adjustment of the dosing of the insulin administrations corresponding to the assigned class; and controlling an insulin administration device to adjust the dosing of the insulin administration in response to the recommendation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 13, 14, 19)
-
-
10. A method for determining a disturbance parameter characterizing a disturbance of a tested glucose metabolism that is manifest despite the administration of insulin to adjust dosing of insulin administration, the method comprising:
-
relating glucose concentration values g(t1) to g(tn) to time points t1 to tn that are distributed over a period of time of at least four hours; using the glucose concentration values g(t1) to g(tn) as input parameters to a processor to calculate disturbance values w(g(t1)) to w(g(tn)) as function values of a weight function w, the weight function w being configured to give more weight to a large deviation between the glucose concentration values g(t1) to g(tn) and a target range of glucose concentration values than a small deviation between the glucose concentration values g(t1) to g(tn) and the target range;
wherein for multiple time intervals that are each included in the period of time, the disturbance values of the respective time intervals are used to calculate a respective characteristic disturbance numbers;using the characteristic disturbance numbers to determine the disturbance parameter on a processor, wherein the disturbance parameter characterizes a type and/or severity of a disturbance of the tested glucose metabolism that is manifest despite the administration of insulin; signaling an output unit to output a recommendation for adjustment of a dosing of the insulin administrations corresponding to the type and/or severity of the disturbance; and controlling an insulin administration device to adjust the dosing of the insulin administration in response to the recommendation. - View Dependent Claims (11, 12)
-
-
15. A system for assessment of a series of glucose concentration values of a body fluid of a diabetic for adjustment of the dosing of insulin administrations, the system comprising:
-
a measuring unit comprising a sensor configured to measure glucose concentration values g(t1) to g(tn) for time points t1 to tn that are distributed over a period of time of at least four hours; a memory for storing the concentration values; an analytical unit for analyzing the concentration values; a receiver in communication with the measuring unit and the analytical unit;
the receiver being configured to transfer the measured glucose concentration values from the measuring unit to the analytical unit;wherein the analytical unit is adapted to use the glucose concentration values g(t1) to g(tn) as input parameters to calculate disturbance values w(g(t1)) to w(g(tn)) as function values of a weight function w, determine a disturbance parameter from the disturbance values, and assign the disturbance parameter to one of at least two predetermined classes, each of said classes corresponding to recommendations concerning the optimal dosing of insulin administrations being dedicated such that these recommendations can be provided for adjustment of the dosing of the insulin administrations; wherein the weight function w has a lesser slope in a target range of the glucose concentration values g(t1) to g(tn) than in a range that is adjacent to the target range; and an insulin administration device coupled to the analytical unit, the insulin administration device being controlled by the analytical unit to adjust the dosing of the insulin administration in response to the recommendation corresponding to the assigned predetermined class. - View Dependent Claims (16, 17, 18)
-
Specification