Identification of biological samples

• US 10,207,270 B2
• Filed: 12/09/2016
• Issued: 02/19/2019
• Est. Priority Date: 05/24/2004
• Status: Active Grant

• Current Assignee: Research Instruments Limited (The Cooper Cos., Inc.)
• Original Assignee: Research Instruments Limited (The Cooper Cos., Inc.)
• Inventors: Lansdowne, David Charles
• Primary Examiner(s): Hunnings, Travis R
• Application Number:
  US15/374,607
• Publication Number:
  US 20170087554A1
• Time in Patent Office: 802 Days
• CPC Class Codes: B01L 2300/021 Identification, e.g. bar codes
• CPC Class Codes: B01L 2300/022 Transponder chips
• CPC Class Codes: B01L 2300/023 Sending and receiving of information, e.g. using bluetooth
• CPC Class Codes: B01L 3/545 for laboratory containers
• CPC Class Codes: B01L 7/04 Heat insulating devices, e.g. jackets for flasks
• CPC Class Codes: B01L 9/02 Laboratory benches or tables; Fittings therefor
• CPC Class Codes: G01N 2035/00782 reprogrammmable code
• CPC Class Codes: G01N 35/00732 Identification of carriers, materials or components in automatic analysers
• CPC Class Codes: G06K 7/10326 the antenna being of the very-near field type, e.g. capacitive
• CPC Class Codes: G06K 7/10366 the interrogation device being adapted for miscellaneous applications

Abstract

A method for coding and identification of biological samples for in vitro fertilization comprises the steps of applying to receptacles intended for unfertilized eggs and sperm, respectively, an identification code characteristic of the patient; placing unfertilized eggs and sperm, respectively, in the receptacles; storing, transporting and admixing the respective samples in receptacles which each carry the same code; and implanting the resulting embryo in the patient. The identification code may based on RFID technology, in which sample vessels (12) are codified by the application of an RFID tag (13).

Claims

1. A method for preparing and identifying biological samples for in vitro fertilisation, the method comprising:

applying to at least one receptacle intended for unfertilised eggs or sperm, an identification code associated with a patient, the identification code being stored on a radio frequency identification (RFID) tag configured to be accessible by a reader associated with a laboratory bench;

transmitting, by an antenna associated with the laboratory bench, activation radiation to the RFID tag of the at least one receptacle;

reading, by the reader associated with the laboratory bench, the identification code provided by a signal emitted by the RFID tag of the at least one receptacle;

placing unfertilised eggs or sperm in the at least one receptacle; and

storing the at least one receptacle which carries the identification code.

2. The method according to claim 1, wherein information relating to the at least one receptacle and a sample stored therein is maintained in a database.

3. The method according to claim 2, wherein the database is controlled by software which includes an anti-collision protocol to discriminate between data received from a plurality of receptacles having different identification codes attached thereto.

4. The method according to claim 1, wherein the antenna configured to transmit activation radiation and receive a signal emitted by the RFID tag is located beneath a surface of the laboratory bench.

5. The method of claim 1, further comprising

retrieving, from a database, patient identification information associated with the at least one receptacle;

and

presenting, on a display associated with the laboratory bench, patient identification information associated with the at least one receptacle.

6. The method of claim 1, further comprising tuning, by an adjustable capacitor associated with the laboratory bench, a coupling resonance between the antenna and the RFID tag of the at least one receptacle.

7. The method of claim 1, further comprising heating the at least one receptacle by a heater associated with the laboratory bench.

8. The method of claim 1, wherein the antenna and associated transmission equipment are distributed about the laboratory bench.

9. A system comprising:

a laboratory bench comprising a work area for preparing and identifying biological samples for in vitro fertilization;

an apparatus associated with the laboratory bench, the apparatus comprising;

an antenna configured to transmit an activation signal to a radio frequency identification (RFID) tag of an in vitro fertilization biological sample vessel, the RFID tag storing an identification code associated with a patient, and configured to receive signals emitted by the RFID tag of the in vitro fertilization biological sample vessel, and

a reader configured to read the identification code provided by a received signal emitted by the RFID tag of the in vitro fertilization biological sample vessel; and

a database configured to store or retrieve information associated with the in vitro fertilization biological sample vessel.

10. The system of claim 9, wherein the laboratory bench comprises a computing device configured to communicate with the database.

11. The system of claim 9, wherein the work area is configured to be warmed to a controlled temperature to maintain viability of the biological samples.

12. The system of claim 9, wherein the work area comprises at least one plate set into a surface of the laboratory bench, the at least one plate having a top surface and a bottom surface.

13. The system of claim 12, wherein the at least one plate is electrically-insulating.

14. The system of claim 12, wherein the antenna is configured to transmit activation radiation to and receive signals emitted by the RFID tag of the in vitro fertilization biological sample vessel through the at least one plate.

15. The system of claim 9, further comprising a power supply comprising a transformer, wherein the transformer is configured to minimize an impedance mismatch between the reader and the antenna.

16. The system of claim 9, further comprising an adjustable resistor configured to dampen a magnetic field produced by the antenna over a surface of the laboratory bench.

17. The system of claim 9, wherein the RFID tag is incorporated in the sample vessel.

18. The system of claim 9, wherein the RFID tag is attached to the sample vessel.

19. The system of claim 9, further comprising an adjustable capacitor configured to tune a coupling resonance between the antenna and the RFID tag of the in vitro fertilization biological sample vessel.