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Etanercept formulations stabilized with xylitol

  • US 10,213,508 B2
  • Filed: 09/26/2017
  • Issued: 02/26/2019
  • Est. Priority Date: 10/18/2011
  • Status: Expired due to Fees
First Claim
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1. A stabilized aqueous pharmaceutical composition comprisinga) etanercept,b) buffer, andc) stabilizer comprising 6 to 10 weight % xylitol,wherein the composition has a pH of 6.0 to 6.6, or a pH within 10 percent of 6.0 and 6.6 and is free or essentially free of arginine.

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