End effector including an implantable arrangement

  • US 10,258,330 B2
  • Filed: 06/22/2015
  • Issued: 04/16/2019
  • Est. Priority Date: 09/30/2010
  • Status: Active Grant
First Claim
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1. An end effector, comprising:

  • a first jaw;

    a second jaw, wherein at least one of said first jaw and said second jaw is movable to compress tissue between said first jaw and said second jaw;

    an implantable arrangement comprising a first layer and a second layer, wherein said first layer and said second layer comprise a polymeric composition;

    a plurality of first cavities defined in said first layer, wherein said first cavities interconnectedly form a permeable first layer, wherein said first cavities releasably retain a first therapeutic agent, and wherein said first therapeutic agent is configured to induce a first biological response in the tissue; and

    a plurality of second cavities defined in said second layer, wherein said second cavities interconnectedly form a permeable second layer, wherein said second cavities releasably retain a second therapeutic agent, and wherein said second therapeutic agent is configured to induce a second biological response in the tissue, wherein said first therapeutic agent and said second therapeutic agent are different, and wherein said first cavities and said second cavities are separate and distinct from one another.

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