Detecting blockage of a reservoir cavity during a seating operation of a fluid infusion device

• US 10,275,572 B2
• Filed: 05/01/2014
• Issued: 04/30/2019
• Est. Priority Date: 05/01/2014
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Inventors: Alderete, Jr., Juan M., Campbell, Alexander S., Chow, Steve, Kow, Hsiao-Yu S., Monirabbasi, Salman, Sokolovskyy, Dmytro Y., Weaver, Andrew E.
• Primary Examiner(s): Mehta, Bhisma
• Assistant Examiner(s): Frehe, William R
• Application Number:
  US14/267,696
• Publication Number:
  US 20150314068A1
• Time in Patent Office: 1,825 Days
• CPC Class Codes: A61M 2205/332 Force measuring means
• CPC Class Codes: A61M 5/14216 Reciprocating piston type
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/63 for local operation

Abstract

A fluid infusion device and related operating methods are presented here. An exemplary embodiment of the device includes a drive motor assembly, a force sensor associated with the drive motor assembly, and a reservoir cavity that accommodates fluid reservoirs. An exemplary operating method for the device obtains force measurements for a reservoir seating action of the drive motor assembly, where the force measurements indicate measures of force imparted to the force sensor during the reservoir seating action. The method continues by determining that a vent in the reservoir cavity is blocked, based on an analysis of the force measurements, and by initiating corrective action for the fluid infusion device in response to determining that the vent in the reservoir cavity is blocked.

Claims

1. A method of operating a fluid infusion device comprising a drive motor assembly, a force sensor associated with the drive motor assembly, a reservoir cavity that accommodates a fluid reservoir having a piston, and an actuator coupled to the drive motor assembly to actuate the piston, the method comprising:

obtaining a plurality of force measurements during a reservoir seating action of the drive motor assembly, the plurality of force measurements indicating measures of force imparted to the force sensor during the reservoir seating action;

comparing an initial force measurement from the plurality of force measurements to an early detection threshold force value;

initiating an analysis of additional force measurements from the plurality of force measurements only when the initial force measurement is greater than the early detection threshold force value;

determining that a vent for equalizing air pressure inside the reservoir cavity is blocked and preventing air in the reservoir cavity from venting externally, based on the analysis of the additional force measurements, wherein the determining occurs before actual seating of the actuator in contact with the piston; and

initiating corrective action for the fluid infusion device in response to determining that the vent in the reservoir cavity is blocked.

2. The method of claim 1, wherein initiating corrective action comprises terminating the reservoir seating action.

3. The method of claim 1, wherein initiating corrective action comprises generating a user alert at the fluid infusion device.

4. The method of claim 1, further comprising:

obtaining a plurality of distance measurements during the reservoir seating action;

calculating a slope of force-versus-distance for the plurality of distance measurements; and

comparing the calculated slope of force-versus-distance to a threshold slope value, wherein the method determines that the vent in the reservoir cavity is blocked when the calculated slope is greater than the threshold slope value.

5. The method of claim 1, wherein:

obtaining the plurality of force measurements comprises obtaining a first force measurement corresponding to a first distance measurement associated with the drive motor assembly, and obtaining a second force measurement corresponding to a second distance measurement associated with the drive motor assembly; and

the method further comprises calculating a difference between the second force measurement and the first force measurement, wherein the method determines that the vent in the reservoir cavity is blocked when the calculated difference is greater than a threshold force value.

6. The method of claim 1, further comprising:

filtering the obtained plurality of force measurements to reduce high frequency characteristics, wherein the determining is based on an analysis of the filtered force measurements.

7. The method of claim 1, further comprising:

acquiring a reservoir filling measurement for the fluid reservoir;

calculating an anticipated travel distance for seating the piston of the fluid reservoir, based on the acquired reservoir filling measurement;

ascertaining, before the anticipated travel distance is reached, that the initial force measurement is greater than the early detection threshold force value; and

generating an alert in response to the ascertaining.

8. The method of claim 1, further comprising:

detecting a pre-seating force value during the reservoir seating action;

recording a first distance measurement corresponding to the detected pre-seating force value;

thereafter, detecting an expected seating force value during the reservoir seating action;

recording a second distance measurement corresponding to the detected expected seating force value;

calculating a difference between the second distance measurement and the first distance measurement; and

generating an alert when the difference is greater than a threshold seating distance.

9. The method of claim 1, further comprising:

pausing the reservoir seating action;

obtaining the initial force measurement while the reservoir seating action is paused; and

generating an alert when the initial force measurement is greater than the early detection threshold force value.

10. The method of claim 1, further comprising:

recording a first force measurement during the reservoir seating action;

after recording the first force measurement, rewinding the drive motor assembly to achieve a rewound position;

recording a second force measurement while the drive motor assembly is in the rewound position; and

generating an alert when the second force measurement is less than the first force measurement by at least a threshold amount.

11. A method of operating a fluid infusion device comprising a drive motor assembly, an actuator coupled to the drive motor assembly, and a reservoir that accommodates a fluid reservoir having a piston, the method comprising:

initiating a reservoir seating action intended to seat the actuator with the piston of the fluid reservoir;

obtaining, for each of a plurality of travel distance measurement points associated with the reservoir seating action, a respective force measurement that is indicative of air pressure inside the reservoir cavity, resulting in a plurality of obtained force measurements;

comparing an initial force measurement from the plurality of obtained force measurements to an early detection threshold force value;

initiating processing of additional force measurements from the plurality of obtained force measurements and for at least two of the plurality of travel distance measurement points only when the initial force measurement is greater than the early detection threshold force value;

determining that a vent for equalizing air pressure inside the reservoir cavity is blocked and preventing air in the reservoir cavity from venting externally, based on the processing of the additional force measurements, wherein the determining occurs before actual seating of the actuator in contact with the piston; and

initiating corrective action for the fluid infusion device in response to determining that the vent in the reservoir cavity is blocked.

12. The method of claim 11, wherein initiating corrective action comprises generating an alert at the fluid infusion device.

13. The method of claim 11, wherein the processing comprises:

calculating a slope of force-versus-distance for the additional force measurements; and

comparing the calculated slope of force-versus-distance to a threshold slope value, wherein the method determines that the vent in the reservoir cavity is blocked when the calculated slope is greater than the threshold slope value.

14. The method of claim 11, wherein the processing comprises:

calculating a difference between a first force measurement and a second force measurement, wherein the method determines that the vent in the reservoir cavity is blocked when the calculated difference is greater than a threshold force value.

15. The method of claim 11, further comprising:

filtering the plurality of obtained force measurements to reduce high frequency characteristics, wherein the processing is performed on filtered force measurements.

16. The method of claim 11, further comprising:

acquiring a reservoir filling measurement for the fluid reservoir;

calculating an anticipated travel distance for seating the actuator with the piston of the fluid reservoir, based on the acquired reservoir filling measurement;

ascertaining, before the anticipated travel distance is reached, that the initial force measurement is greater than the early detection threshold force value; and

generating an alert in response to the ascertaining.

17. The method of claim 11, further comprising:

detecting a pre-seating force value during the reservoir seating action;

recording a first distance measurement corresponding to the detected pre-seating force value;

thereafter, detecting an expected seating force value during the reservoir seating action;

recording a second distance measurement corresponding to the detected expected seating force value;

calculating a difference between the second distance measurement and the first distance measurement; and

generating an alert when the difference is greater than a threshold seating distance.

18. The method of claim 11, further comprising:

pausing the reservoir seating action;

obtaining the initial force measurement while the reservoir seating action is paused; and

generating an alert when the initial force measurement is greater than the early detection threshold force value.

19. The method of claim 11, further comprising:

recording a first force measurement during the reservoir seating action;

after recording the first force measurement, rewinding the actuator to achieve a rewound position;

recording a second force measurement while the actuator is in the rewound position; and

generating an alert when the second force measurement is less than the first force measurement by at least a threshold amount.

20. A device for delivering fluid to a user, the device comprising:

a housing;

a reservoir cavity within the housing to accommodate fluid reservoirs;

a drive motor assembly in the housing to advance an actuator for a piston of a fluid reservoir;

a force sensor associated with the drive motor assembly to generate output levels in response to force imparted thereto, the output levels corresponding to force measurements; and

an electronics module coupled to the force sensor to process the output levels during a reservoir seating action intended to seat the actuator with the piston of the fluid reservoir by;

obtaining a plurality of force measurements from the force sensor during the reservoir seating action, the plurality of force measurements indicating measures of force imparted to the force sensor during the reservoir seating action;

comparing an initial force measurement from the plurality of force measurements to an early detection threshold force value;

initiating an analysis of additional force measurements from the plurality of force measurements only when the initial force measurement is greater than the early detection threshold force value;

determining that a vent for equalizing air pressure inside the reservoir cavity is blocked and preventing air in the reservoir cavity from venting externally, based on the analysis of the additional force measurements, wherein the determining occurs before actual seating of the actuator in contact with the piston; and

initiating corrective action for the fluid infusion device in response to determining that the vent in the reservoir cavity is blocked.

21. The device of claim 20, wherein the electronics module initiates the corrective action by generating a user alert.

22. The device of claim 20, wherein, during the reservoir seating action, the electronics module:

obtains a plurality of distance measurements;

calculates a slope of force-versus-distance for the plurality of distance measurements; and

compares the calculated slope of force-versus-distance to a threshold slope value, wherein the electronics module determines that the vent in the reservoir cavity is blocked when the calculated slope is greater than the threshold slope value.

23. The device of claim 20, wherein, during the reservoir seating action, the electronics module:

obtains a first force measurement corresponding to a first distance measurement associated with the drive motor assembly;

obtains a second force measurement corresponding to a second distance measurement associated with the drive motor assembly; and

calculates a difference between the second force measurement and the first force measurement, wherein the electronics module determines that the vent in the reservoir cavity is blocked when the calculated difference is greater than a threshold force value.

24. The device of claim 20, wherein:

the electronics module filters the obtained plurality of force measurements to reduce high frequency characteristics; and

the determination made by the electronics module is based on an analysis of the filtered force measurements.