System and method for modifying medicament delivery parameters after a site change

• US 10,279,105 B2
• Filed: 12/23/2014
• Issued: 05/07/2019
• Est. Priority Date: 12/26/2013
• Status: Active Grant

• Current Assignee: Tandem Diabetes Care Incorporated
• Original Assignee: Tandem Diabetes Care Incorporated
• Inventors: Rosinko, Michael
• Primary Examiner(s): Eisenberg, Rebecca E
• Application Number:
  US14/581,398
• Publication Number:
  US 20150182693A1
• Time in Patent Office: 1,596 Days
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 2205/52 with memories providing a history of measured variating parameters of apparatus or patient
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

Apparatuses and methods for delivery of medicaments such as insulin disclosed herein can increase the effectiveness of therapy by adjusting medicament delivery parameters to account for the loss of medicament absorption upon delivering medicament at a new insertion site. When a needle is inserted at a new site on a patient'"'"'s body for delivery of medicament to that patient, a natural inflammatory response by the body to insertion of the needle causes the body to resist absorption of the delivered medicament. However, this medicament resistance decreases over time. Embodiments of the invention therefore adjust medicament delivery to deliver less medicament as time passes after an infusion set change causes medicament to be delivered at a new insertion site.

Claims

1. A portable infusion pump, comprising:

a pump device configured to deliver medicament to a user through an infusion set in fluid communication with the pump device and physically connected to the user'"'"'s body; and

a processor communicatively coupled to the pump device to control the pump device to deliver the medicament to the user, the processor further configured to;

determine that a first infusion set has been detached from fluid communication with the pump device and a second infusion set has subsequently been placed into fluid communication with the pump device;

initiate delivery of medicament with the pump device through the second infusion set; and

adjust delivery of medicament with the pump device through the second infusion set based on a time since initiating delivery of medicament through the second infusion set to account for changes in medicament absorption over time at an insertion site of the second infusion set.

2. The portable infusion pump of claim 1, wherein automatically adjusting delivery of medicament with the pump device based on a time since initiating delivery of medicament through the second infusion set includes reducing an amount of medicament delivered with the pump device as the time since initiating delivery increases.

3. The portable infusion pump of claim 1, wherein the processor is further configured to determine delivery of medicament with the pump device based on one or more medicament delivery parameters, and wherein automatically adjusting delivery of medicament with the pump device based on a time since initiating delivery of medicament includes adjusting a medicament delivery parameter.

4. The portable infusion pump of claim 3, wherein the medicament delivery parameter is a basal rate.

5. The portable infusion pump of claim 4, wherein automatically adjusting delivery of medicament includes decreasing the basal rate.

6. The portable infusion pump of claim 3, wherein the medicament delivery parameter is a carbohydrate ratio.

7. The portable infusion pump of claim 6, wherein automatically adjusting delivery of medicament includes decreasing the carbohydrate ratio.

8. The portable infusion pump of claim 3, wherein the medicament delivery parameter is an insulin sensitivity.

9. The portable infusion pump of claim 8, wherein automatically adjusting delivery of medicament includes increasing the insulin sensitivity.

10. The portable infusion pump of claim 1, further comprising a user interface, and wherein the processor is further configured to determine that the first infusion set has been detached from fluid communication with the pump device and the second infusion set has subsequently been placed into fluid communication with the pump device through an indication received through the user interface.

11. The portable infusion pump of claim 1, wherein the processor is configured to automatically determine that the first infusion set has been detached from fluid communication with the pump device and the second infusion set has subsequently been placed into fluid communication with the pump device.

12. The portable infusion pump of claim 1, wherein the medicament is insulin.

13. A portable infusion pump, comprising:

a cartridge including a reservoir of medicament and an outlet port selectively coupleable to an infusion set for delivery of the medicament to the user;

a pump device configured to selectively receive the cartridge, the pump device configured to selectively cause the medicament to be delivered from the reservoir through the infusion set to the user; and

a processor communicatively coupled to the pump device, the processor configured to;

determine that a first infusion set has been detached from the cartridge and a second infusion set has subsequently been placed into attached to the cartridge;

initiate delivery of medicament with the pump device through the second infusion set; and

adjust delivery of medicament with the pump device through the second infusion set based on a time since initiating delivery of medicament through the second infusion set to account for changes in medicament absorption over time at an insertion site of the second infusion set.

14. The portable infusion pump of claim 13, wherein automatically adjusting delivery of medicament with the pump device based on a time since initiating delivery of medicament through the second infusion set includes reducing an amount of medicament delivered with the pump device as the time since initiating delivery increases.

15. The portable infusion pump of claim 13, wherein the processor is further configured to determine delivery of medicament with the pump device based on one or more medicament delivery parameters, and wherein automatically adjusting delivery of medicament with the pump device based on a time since initiating delivery of medicament includes adjusting a medicament delivery parameter.

16. The portable infusion pump of claim 15, wherein the medicament delivery parameter is a basal rate.

17. The portable infusion pump of claim 16, wherein automatically adjusting delivery of medicament includes decreasing the basal rate.

18. The portable infusion pump of claim 15, wherein the medicament delivery parameter is a carbohydrate ratio.

19. The portable infusion pump of claim 18, wherein automatically adjusting delivery of medicament includes decreasing the carbohydrate ratio.

20. The portable infusion pump of claim 15, wherein the medicament delivery parameter is an insulin sensitivity.

21. The portable infusion pump of claim 20, wherein automatically adjusting delivery of medicament includes increasing the insulin sensitivity.

22. The portable infusion pump of claim 13, further comprising a user interface, and wherein the processor is further configured to determine that the first infusion set has been detached from fluid communication with the pump device and the second infusion set has subsequently been placed into fluid communication with the pump device through indication received through the user interface.

23. The portable infusion pump of claim 13, wherein the processor is configured to automatically determine that the first infusion set has been detached from fluid communication with the pump device and the second infusion set has subsequently been placed into fluid communication with the pump device.

24. The portable infusion pump of claim 13, wherein the medicament is insulin.