Systems and methods for detecting intrathecal penetration

• US 10,279,183 B2
• Filed: 04/27/2016
• Issued: 05/07/2019
• Est. Priority Date: 09/30/2010
• Status: Active Grant

• Current Assignee: Nevro Corporation
• Original Assignee: Nevro Corporation
• Inventors: Parker, Jon, Thacker, James R.
• Primary Examiner(s): Dougherty, Sean P
• Application Number:
  US15/140,039
• Publication Number:
  US 20160354609A1
• Time in Patent Office: 1,105 Days
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36142 for improving safety

Abstract

Systems and methods for detecting intrathecal penetration are disclosed. A method in accordance with one embodiment includes detecting a value corresponding to an impedance of an electrical circuit that in turn includes an electrical contact located within the patient, and patient tissue adjacent to the electrical contact. The method further includes comparing the detected value to a predetermined criterion, and, if the detected value meets the predetermined criterion, identifying penetration of the patient'"'"'s dura based at least in part on the detected value.

Claims

1. A computer-readable medium for use with a patient, having instructions that, when executed:

receive information corresponding to an impedance measured between two electrical contacts, carried by a signal delivery device, and intervening patient tissue adjacent to the electrical contacts;

compare the information to a predetermined criterion;

if the information meets the predetermined criterion, provide an indication that the patient'"'"'s dura has been penetrated; and

if the information does not meet the predetermined criterion, cause a pulse generator to generate a neural modulation signal to be delivered to the patient via the signal delivery device.

2. The computer-readable medium of claim 1 wherein the indication is a first indication, and wherein the instructions, when executed:

provide a second indication, indicating that the patient'"'"'s dura has not been penetrated, in response to the information not meeting the predetermined criterion.

3. The computer-readable medium of claim 1 wherein the neural modulation signal has a frequency of from about 3 kHz to about 50 kHz.

4. The computer-readable medium of claim 1 wherein the predetermined criterion includes a reference impedance of about 50 ohms or less.

5. The computer-readable medium of claim 1 wherein the predetermined criterion includes a reference impedance of about 200 ohms or less.

6. The computer-readable medium of claim 1 wherein the indication includes an indication presented at a display device.

7. The computer-readable medium of claim 1 wherein the indication includes an aural indication.

8. A computer-readable medium for use with a patient, having instructions that, when executed:

receive information corresponding to an impedance determined between electrical contacts carried by a signal delivery device, and intervening patient tissue adjacent to the electrical contacts; and

if the information meets a predetermined criterion, provide an indication that the patient'"'"'s dura has been penetrated;

or

if the information does not meet the predetermined criterion, cause a neural modulation signal to be delivered to the patient via the signal delivery device.

9. The computer-readable medium of claim 8 wherein the neural modulation signal has a frequency of from about 3 kHz to about 50 kHz.

10. The computer-readable medium of claim 8 wherein the signal delivery device is coupleable to a pulse generator, wherein the indication is a first indication, and wherein the instructions, when executed, provide a second indication, indicating that the patient'"'"'s dura has been penetrated, in response to the information not meeting the predetermined criterion.

11. The computer-readable medium of claim 8 wherein the predetermined criterion includes a reference impedance of about 50 ohms or less.

12. The computer-readable medium of claim 8 wherein the predetermined criterion includes a reference impedance of about 200 ohms or less.

13. A computer-readable medium for use with a patient, having instructions that, when executed:

receive information corresponding to an impedance measured between electrical contacts carried by a signal delivery device, and intervening patient tissue adjacent to the electrical contacts;

compare the information to a predetermined criterion;

if the information meets the predetermined criterion, provide an indication that the patient'"'"'s dura has been penetrated, wherein the predetermined criterion includes a reference impedance of 50 ohms or less; and

if the information does not meet the predetermined criterion, cause a neural modulation signal to be delivered to the patient via the signal delivery device.

14. The computer-readable medium of claim 13 wherein the indication is a first indication, and wherein the instructions, when executed:

provide a second indication indicating that the patient'"'"'s dura has not been penetrated, in response to the information not meeting the predetermined criterion.

15. The computer-readable medium of claim 13 wherein the neural modulation signal has a frequency of from about 3 kHz to about 50 kHz.