Tissue matrices and methods of treatment

• US 10,307,237 B2
• Filed: 04/27/2016
• Issued: 06/04/2019
• Est. Priority Date: 05/15/2015
• Status: Active Grant

• Current Assignee: Lifecell Corporation (Abbvie Incorporated)
• Original Assignee: Lifecell Corporation (Abbvie Incorporated)
• Inventors: Wang, Kai-Roy, Park, Sangwook, Barere, Aaron
• Primary Examiner(s): Mathew, Seema
• Application Number:
  US15/139,458
• Publication Number:
  US 20160331504A1
• Time in Patent Office: 1,133 Days
• CPC Class Codes: A61B 90/02 Devices for expanding tissue, e.g. skin tissue implements for holding wounds open, surgical tractors A61B17/02; implantable mammary prosthesis A61F2/12; dilators A61M29/00
• CPC Class Codes: A61F 2/0063 Implantable repair or support meshes, e.g. hernia meshes
• CPC Class Codes: A61F 2/12 Mammary prostheses and implants
• CPC Class Codes: A61F 2002/0068 having a special mesh pattern
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61L 2430/04 for mammary reconstruction
• CPC Class Codes: A61L 27/3666 Epithelial tissues other than skin

Abstract

Methods, systems, and compositions for treatment are provided. The methods can be used to stretch and completely or nearly completely wrap a composition around an implant or tissue expander. The systems can be used to protect an implant or tissue expander by completely or nearly completely wrapping a composition around the implant or tissue expander. The compositions can be used to completely or nearly completely wrap around an implant or tissue expander to provide support and protection to the implant or tissue expander.

Claims

1. A method of treatment, comprising:

providing a composition, the composition including a tissue matrix or synthetic material defining a composition body, the composition body including a central region and at least two extensions having a mesh pattern formed therein, the at least two extensions protruding from opposing sides of the central region;

positioning the composition onto an implant or a tissue expander with the central region of the composition disposed against an anterior side of the implant or the tissue expander;

stretching and expanding the at least two extensions at the mesh pattern to wrap the composition around the implant or tissue expander such that one extension of the at least two extensions is wrapped in a first direction around the implant or tissue expander and another extension of the at least two extensions is wrapped in an opposing direction to secure the composition to the implant or tissue expander; and

engaging the at least two extensions with each other at a posterior side of the implant or the tissue expander, the posterior side opposing the anterior side of the implant or the tissue expander.

2. The method of claim 1, wherein the tissue matrix is a tissue matrix sheet defining a planar and flexible configuration.

3. The method of claim 1, wherein the tissue matrix is an acellular tissue matrix.

4. The method of claim 1, wherein the composition comprises at least two additional extensions protruding from opposing sides of the central region.

5. The method of claim 4, wherein the at least two additional extensions each comprise a mesh pattern formed therein.

6. The method of claim 1, wherein the central region comprises a mesh pattern formed therein.

7. The method of claim 1, comprising interlocking the at least two extensions of the composition with a fastening element to secure the composition to the implant.

8. The method of claim 7, wherein the fastening element detachably interlocks the at least two extensions of the composition.

9. The method of claim 7, wherein the fastening element includes an elongated body with a proximal end and a distal end, the proximal end including a rounded tip.

10. The method of claim 9, wherein a diameter of the rounded tip is dimensioned greater than a width of the elongated body.

11. The method of claim 9, wherein the rounded tip includes a slit configured to receive therethrough the distal end of the fastening element to interlock the fastening element to the two extensions.

12. The method of claim 1, wherein the at least two extensions extend parallel to each other.

13. The method of claim 1, wherein the central region of the composition is mesh-free.

14. The method of claim 1, wherein:

the composition body includes a horizontal axis passing through the central region, the at least two extensions protruding from the opposing sides of the central region and substantially parallel to the horizontal axis;

the composition body includes a vertical axis passing through the central region; and

the composition body includes two additional extensions protruding from opposing sides of the central region and substantially parallel to the vertical axis.