Self-expanding heart valves for coronary perfusion and sealing

• US 10,321,993 B2
• Filed: 05/20/2015
• Issued: 06/18/2019
• Est. Priority Date: 05/21/2014
• Status: Active Grant

• Current Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: St. Jude Medical Cardiology Division Incorporated (Abbott Laboratories Incorporated)
• Inventors: Li, Xue Mei, Alkhatib, Yousef F.
• Primary Examiner(s): Prebilic, Paul B
• Application Number:
  US15/312,360
• Publication Number:
  US 20170079786A1
• Time in Patent Office: 1,490 Days
• Field of Search: 623 124- 126
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2230/001 Figure-8-shaped, e.g. hourglass-shaped
• CPC Class Codes: A61F 2230/0013 Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
• CPC Class Codes: A61F 2250/0037 differing in height or in length
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0069 Sealing means

Abstract

A prosthetic heart valve includes a collapsible and expandable stent including a plurality of struts forming cells, the stent having a proximal end, a distal end, an annulus section adjacent the proximal end, an aortic section adjacent the distal end, and a transition section disposed between the annulus section and the aortic section, the aortic section having a larger diameter than the annulus section. The heart valve further includes a valve assembly disposed entirely in the annulus section of the stent for controlling the flow of blood through the stent, the valve assembly including a plurality of leaflets, and a cuff, the cuff being disposed on a surface of the stent and extending fully over at least two rows of cells of the stent.

Claims

1. A prosthetic heart valve, comprising:

a collapsible and expandable stent including a plurality of struts forming cells arranged in annular rows and a plurality of commissure features circumferentially spaced about the stent in a predetermined one of the annular rows, the stent having a proximal end, a distal end, an annulus section adjacent the proximal end, an aortic section adjacent the distal end and having a larger diameter than the annulus section, and a transition section disposed between the annulus section and the aortic section, the transition section including a plurality of axial struts oriented parallel to a longitudinal axis of the stent and circumferentially spaced between the plurality of commissure features when the stent is in an expanded condition, the plurality of axial struts being disposed in the predetermined one of the annular rows and extending into the annulus section such that a proximal end of each of the axial struts is located closer to a proximal end of the stent than a proximal end of each of the commissure features is located to the proximal end of the stent, the stent having at least two annular rows of cells provided proximally of the proximal ends of the axial struts, a first one of the at least two rows including cells of a first size and a second one of the at least two rows including cells of a second size smaller than the first size, the plurality of axial struts being connected to the cells of the second size; and

a valve assembly disposed entirely in the annulus section of the stent for controlling the flow of blood through the stent, the valve assembly including a plurality of leaflets, and a cuff, the cuff being disposed on a surface of the stent and extending fully over the at least two rows of cells.

2. The prosthetic heart valve of claim 1, wherein the cuff is disposed on a luminal surface of the stent.

3. The prosthetic heart valve of claim 1, wherein the cuff is disposed on an abluminal surface of the stent.

4. The prosthetic heart valve of claim 1, wherein the second one of the at least two rows of cells includes a plurality of primary cells, the primary cells being larger than the cells of the second size, each of the primary cells being disposed directly below one of the commissure features of the stent.

5. The prosthetic heart valve of claim 1, wherein the stent includes three of the commissure features.

6. The prosthetic heart valve of claim 1, wherein the first one of the at least two rows of cells is adjacent the proximal end of the stent.

7. The prosthetic heart valve of claim 1, wherein cells in the transition section of the stent remain uncovered by the cuff to allow blood flow therethrough.

8. The prosthetic heart valve of claim 1, wherein cells in the transition section are larger than cells in the annulus section.

9. The prosthetic heart valve of claim 1, wherein the transition section includes cells having an asymmetric shape.

10. The prosthetic heart valve of claim 1, wherein the transition section includes multiple groups of cells, each group being disposed between adjacent commissure features and including a hexagonal cell and two asymmetric cells having an odd number of struts.

11. The prosthetic heart valve of claim 1, wherein the cells of the second size include a first group of struts with a first length and a second group of struts with a length less than the first length and the plurality of axial struts are coupled to struts in the second group.

12. The prosthetic heart valve of claim 1, wherein each of the axial struts has a length that is greater than a length of one of the plurality of commissure features.

13. The prosthetic heart valve of claim 1, wherein the transition section includes multiple groups of cells, each group being disposed between adjacent commissure features and including three hexagonal cells.

14. The prosthetic heart valve of claim 1, further comprising an auxiliary strut disposed below each of the plurality of commissure features.

15. The prosthetic heart valve of claim 14, wherein the cells of the second size include a first group of struts with a first length and a second group of struts with a length less than the first length, the struts in the second group being coupled to at least one of the plurality of axial struts or to one of the auxiliary struts.

16. The prosthetic heart valve of claim 14, wherein each of the axial struts has a length that is equal to the sum of a length of one of the plurality of commissure features and a length of one of the auxiliary struts.