Systems for monitoring and applying electrical currents in an organ perfusion system
First Claim
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1. A system for monitoring the electrical activity of an explanted organ, the system comprising:
- an organ chamber assembly configured to contain an explanted heart;
a first electrode placed in the aortic bloodstream conduit outside the organ chamber assembly;
a second electrode placed epicardially on the heart within the organ chamber assembly;
a third electrode placed epicardially on the heart within the organ chamber assembly;
a controller configured to provide an interface between at least one of the first, second, and third electrode and a defibrillation source wherein the controller receives signals from at least one of the first, second, and third electrode;
a perfusion fluid; and
a heater assembly that heats the perfusion fluid to a temperature between 26° and
37°
C.
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Abstract
Electrode systems have been developed for use in perfusion systems to measure the electrical activity of an explanted heart and to provide defibrillation energy as necessary. The perfusion systems maintain the heart in a heating state at, or near, normal physiological conditions; circulating oxygenated, nutrient enriched perfusion fluid to the heart at or near physiological temperature, pressure and flow rate. These systems include a pair of electrodes that are placed epicardially on the right atrium and left ventricle of the explanted heart, as well as an electrode placed in the aortic blood path.
240 Citations
3 Claims
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1. A system for monitoring the electrical activity of an explanted organ, the system comprising:
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an organ chamber assembly configured to contain an explanted heart; a first electrode placed in the aortic bloodstream conduit outside the organ chamber assembly; a second electrode placed epicardially on the heart within the organ chamber assembly; a third electrode placed epicardially on the heart within the organ chamber assembly; a controller configured to provide an interface between at least one of the first, second, and third electrode and a defibrillation source wherein the controller receives signals from at least one of the first, second, and third electrode; a perfusion fluid; and a heater assembly that heats the perfusion fluid to a temperature between 26° and
37°
C. - View Dependent Claims (2, 3)
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Specification