Inhibition of HIV infection through chemoprophylaxis

  • US 10,335,423 B2
  • Filed: 03/06/2018
  • Issued: 07/02/2019
  • Est. Priority Date: 02/03/2006
  • Status: Active Grant
First Claim
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1. A process of protecting a primate host from a self-replicating infection by an immunodeficiency retrovirus comprising:

  • (a) selecting a primate host not infected with the immunodeficiency retrovirus, and(b) administering directly to the primate host a combination comprising;

    i. a pharmaceutically effective amount of emtricitabine; and

    ii. a pharmaceutically effective amount of tenofovir or a tenofovir prodrug,wherein the combination is administered orally prior to the exposure of the primate host to the immunodeficiency retrovirus,thereby protecting the primate host from infection with the immunodeficiency retrovirus.

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