Pyrimido[4,5-B]indole derivatives and use thereof in the expansion of hematopoietic stem cells
1. A compound of general formula I or II
Pyrimido[4,5-b]indole derivatives are provided. These compounds are useful to expand hematopoietic stem cell populations, particularly, human hematopoietic stem cell populations. The compounds are also useful in the medical treatment of diseases that involve hematopoietic stem cells.
- 1. A compound of general formula I or II
- 3. A method of treating a hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immunodeficiency disease in a subject, comprising administering to the subject in need of such treatment, a compound of general formula I or II