Method and apparatus for detecting electrocardiographic abnormalities based on monitored high frequency QRS potentials

• US 10,342,445 B2
• Filed: 11/03/2016
• Issued: 07/09/2019
• Est. Priority Date: 11/03/2016
• Status: Active Grant

• Current Assignee: Medtronic Monitoring, Inc. (Medtronic Plc)
• Original Assignee: Medtronic Monitoring, Inc. (Medtronic Plc)
• Inventors: Musley, ShaileshKumar V., Shrivastav, Maneesh, Vilendrer, Stacie
• Primary Examiner(s): Tejani, Ankit D
• Application Number:
  US15/342,443
• Publication Number:
  US 20180116538A1
• Time in Patent Office: 978 Days
• Field of Search: None
• CPC Class Codes: A61B 5/259 using conductive adhesive means, e.g. gels
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/316 Modalities, i.e. specific diagnostic methods
• CPC Class Codes: A61B 5/332 Portable devices specially adapted therefor
• CPC Class Codes: A61B 5/363 Detecting tachycardia or bradycardia
• CPC Class Codes: A61B 5/366 Detecting abnormal QRS complex, e.g. widening

Abstract

A system and method of monitoring electrocardiogram (ECG) signals and detecting ischemic conditions. In particular, high-frequency components and low-frequency components are extracted from the monitored ECG signal. The high-frequency components are analyzed to detect reduced amplitude zones (RAZs), while the low-frequency components are utilized to detect premature ventricular contraction (PVC) beats. Potentially ischemic conditions are identified based on both RAZs and PVC beats detected.

Claims

1. A method of detecting ischemia, the method comprising:

sensing an electrocardiogram (ECG) signal;

extracting low-frequency components associated with the sensed ECG signal;

detecting premature ventricular contraction (PVC) beats in the low-frequency components;

incrementing a PVC counter in response to each detected PVC beat on a beat-by-beat basis;

extracting high-frequency components associated with the sensed ECG signal, wherein extracting high-frequency components includes extracting high frequency components associated with QRS complex portions of the sensed ECG signal (HF QRS) and rejecting QRS complex portions associated with detected PVC beats;

detecting a reduced amplitude zone (RAZ) in the HF QRS on a beat-by-beat basis;

incrementing a counter in response to each detected RAZ; and

identifying potential ischemia based on the PVC counter and the RAZ counter.

2. The method of claim 1, wherein extracting high-frequency components includes extracting components in a frequency range of 150-250 Hertz (Hz).

3. The method of claim 1, further including identifying a HF QRS envelope associated with the HF QRS signal.

4. The method of claim 1, wherein potential ischemia is identified when both the PVC counter and the RAZ counter exceed threshold values.

5. The method of claim 1, wherein detecting premature ventricular contraction (PVC) beats in the low-frequency components includes detecting density and/or frequency attributes associated with detected PVC beats.

6. The method of claim 1, wherein identifying potential ischemia based on detection of both RAZs and PVC beats comprises identifying based on an amount of RAZ beats and an amount of PVC beats.

7. The method of claim 1, wherein extracting low-frequency components includes extracting components in a frequency range of 0-40 Hertz (Hz).