Composition having a function for alleviating premenstrual syndrome and menstrual pain

• US 10,342,836 B2
• Filed: 06/19/2014
• Issued: 07/09/2019
• Est. Priority Date: 07/04/2013
• Status: Active Grant

• Current Assignee: Amore Pacific Corporation
• Original Assignee: Amore Pacific Corporation
• Inventors: Kim, Su Hwan, Park, Chan Woong, Jang, Jeong Hwa, Kim, Wan Gi, Lee, Sang Jun
• Primary Examiner(s): Meller, Michael V
• Application Number:
  US14/902,392
• Publication Number:
  US 20160367614A1
• Time in Patent Office: 1,846 Days
• Field of Search: 424725
• CPC Class Codes: A23L 33/105 Plant extracts, their artificial duplicates or their derivatives
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/31 having an effect on comfort perception and well-being
• CPC Class Codes: A23V 2250/1578 Calcium
• CPC Class Codes: A23V 2250/1592 Iron
• CPC Class Codes: A23V 2250/16 Potassium
• CPC Class Codes: A23V 2250/161 Magnesium
• CPC Class Codes: A23V 2250/1642 Zinc
• CPC Class Codes: A23V 2250/2104 Anthocyanins
• CPC Class Codes: A23V 2250/2124 Ginseng
• CPC Class Codes: A23V 2250/702 Vitamin A
• CPC Class Codes: A23V 2250/7042 Vitamin B1
• CPC Class Codes: A23V 2250/7044 Vitamin B2
• CPC Class Codes: A23V 2250/7046 Vitamin B3 niacin
• CPC Class Codes: A23V 2250/7052 Vitamin B6
• CPC Class Codes: A23V 2250/708 Vitamin C
• CPC Class Codes: A23V 2250/714 Vitamin K
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/07 Retinol compounds, e.g. vitamin A retinoic acids A61K31/203
• CPC Class Codes: A61K 31/122 having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
• CPC Class Codes: A61K 31/197 : the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid carnitine A61K31/205
• CPC Class Codes: A61K 31/355 : Tocopherols, e.g. vitamin E
• CPC Class Codes: A61K 31/375 : Ascorbic acid, i.e. vitamin C; Salts thereof
• CPC Class Codes: A61K 31/4415 : Pyridoxine, i.e. Vitamin B6 pyridoxal phosphate A61K31/675
• CPC Class Codes: A61K 31/455 : Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
• CPC Class Codes: A61K 31/51 : Thiamines, e.g. vitamin B1
• CPC Class Codes: A61K 31/519 : ortho- or peri-condensed with heterocyclic rings
• CPC Class Codes: A61K 31/525 : Isoalloxazines, e.g. riboflavins, vitamin B2
• CPC Class Codes: A61K 31/704 : attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin digitoxin A61K31/7048
• CPC Class Codes: A61K 33/00 : Medicinal preparations containing inorganic active ingredients
• CPC Class Codes: A61K 33/06 : Aluminium, calcium or magnesium; Compounds thereof , e.g. clay
• CPC Class Codes: A61K 33/26 : Iron; Compounds thereof
• CPC Class Codes: A61K 33/30 : Zinc; Compounds thereof
• CPC Class Codes: A61K 33/42 : Phosphorus; Compounds thereof
• CPC Class Codes: A61K 36/258 : Panax (ginseng)
• CPC Class Codes: A61P 15/00 : Drugs for genital or sexual disorders for disorders of sex hormones A61P5/24; Contraceptives
• CPC Class Codes: A61P 29/02 : without antiinflammatory effect
• CPC Class Codes: A61P 43/00 : Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The present disclosure relates to a composition containing ginseng fruit extract. The present disclosure also relates to a composition for relieving premenstrual syndrome and menstrual pain, which contains ginseng fruit extract. The composition according to the present disclosure exhibits an effect of relieving or improving the symptoms of premenstrual syndrome and thus can be used as a pharmaceutical composition or a food composition.

Claims

1. A method for relieving premenstrual syndrome or menstrual pain in a human in need thereof comprising administering to said human an effective amount of ginseng fruit ethanol extract, which comprises ginsenosides, vitamin, a mineral and an anthocyanin, and which relieves premenstrual syndrome or menstrual pain in the human in need thereof.

2. The method according to claim 1, wherein the mineral comprises one or more of at least 4000 mg/100 g of potassium, at least 600 mg/100 g of calcium, at least 40 mg/100 g of iron, at least 150 mg/100 g of phosphorus, at least 250 mg/100 g of magnesium and at least 140 mg/100 g of zinc based on the total weight of the extract.

3. The method according to claim 1, wherein the vitamin comprises one or more of at least 150 μ

g/100 g of vitamin A, at least 8 mg/100 g of vitamin B1, at least 5 mg/100 g of vitamin B2, at least 8 mg/100 g of vitamin B6, at least 3 mg/100 g of vitamin C, at least 180 μ

g/100 g of vitamin K, at least 3.5 mg/100 g of niacin, at least 4 mg/100 g of pantothenic acid and at least 250 μ

g/100 g of folic acid based on the total weight of the extract.

4. The method according to claim 1, wherein the ginseng fruit ethanol extract comprises at least 20 ppm of the anthocyanin based on the total weight of the extract.

5. The method according to claim 1, wherein the ginseng fruit ethanol extract comprises 5-30 wt % of ginsenosides based on the total weight of the extract.

6. The method according to claim 1, wherein the ginseng fruit ethanol extract has a weight ratio of protopanaxadiol ginsenoside to protopanaxatriol ginsenoside of 0.1-1.5.

7. The method according to claim 1, wherein the ginseng fruit ethanol extract is present in a composition and the composition comprises 0.01-100 wt % of the ginseng fruit ethanol extract, based on the total weight of the composition.

8. The method according to claim 1, wherein the ginseng fruit ethanol extract comprises at least 20 wt % of crude saponin, based on the total weight of the ginseng fruit extract.

9. The method according to claim 7, wherein the composition is a pharmaceutical composition.

10. The method according to claim 7, wherein the composition is a food composition.