Methods for photodynamic therapy

  • US 10,357,567 B1
  • Filed: 01/12/2018
  • Issued: 07/23/2019
  • Est. Priority Date: 01/12/2018
  • Status: Active Grant
First Claim
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1. A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy, the method comprising:

  • topically applying ALA to a treatment area to be treated with photodynamic therapy;

    after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area; and

    removing the low density polyethylene barrier within 3 hours and then applying light to the treatment area.

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