Monitoring body movement or condition according to motion regimen with conformal electronics

• US 10,383,550 B2
• Filed: 12/21/2016
• Issued: 08/20/2019
• Est. Priority Date: 07/17/2014
• Status: Active Grant

• Current Assignee: Elwha LLC (Intellectual Ventures LLC)
• Original Assignee: Elwha LLC (Intellectual Ventures LLC)
• Inventors: Hyde, Roderick A., Kare, Jordin T., Leuthardt, Eric C., Malamud, Mark A., McKnight, Gary L., Pan, Tony S., Sharadin, Katherine E., Sweeney, Elizabeth A., Tegreene, Clarence T., Whitmer, Charles, Wood, Jr., Lowell L.
• Primary Examiner(s): Abouelela, May A
• Application Number:
  US15/386,470
• Publication Number:
  US 20170164876A1
• Time in Patent Office: 972 Days
• Field of Search: 600300, 600301, 600557, 600587, 600595, 128920
• CPC Class Codes: A61B 2562/0215 Silver or silver chloride containing
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 2562/0261 Strain gauges
• CPC Class Codes: A61B 2562/06 Arrangements of multiple sensors of different types
• CPC Class Codes: A61B 2562/164 the sensor is mounted in or on a conformable substrate or carrier
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/0036 including treatment, e.g., using an implantable medical device, ablating, ventilating
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/024 Detecting, measuring or recording pulse rate or heart rate A61B5/0205, A61B5/021 take precedence
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/1118 Determining activity level
• CPC Class Codes: A61B 5/1121 Determining geometric values, e.g. centre of rotation or angular range of movement
• CPC Class Codes: A61B 5/14542 for measuring blood gases A61B5/14551 takes precedence
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/389 : Electromyography [EMG]
• CPC Class Codes: A61B 5/45 : For evaluating or diagnosing the musculoskeletal system or teeth A61B5/1036, A61B5/1074, A61B7/006 take precedence
• CPC Class Codes: A61B 5/4824 : Touch or pain perception evaluation A61B5/4821 takes precedence
• CPC Class Codes: A61B 5/4833 : Assessment of subject's compliance to treatment
• CPC Class Codes: A61B 5/4836 : Diagnosis combined with treatment in closed-loop systems or methods A61B5/0036 takes precedence
• CPC Class Codes: A61B 5/7275 : Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/7278 : Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence
• CPC Class Codes: A61B 5/7282 : Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/7455 : characterised by tactile indication, e.g. vibration or electrical stimulation
• CPC Class Codes: A61H 23/00 : Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms apparatus for passive exercising A61H1/00; generating or transmitting mechanical vibrations in general B06B
• CPC Class Codes: A61N 1/0456 : Specially adapted for transcutaneous electrical nerve stimulation [TENS]
• CPC Class Codes: A61N 1/0492 : Patch electrodes A61N1/0412, A61N1/0428 take precedence
• CPC Class Codes: A61N 1/36003 : of motor muscles, e.g. for walking assistance
• CPC Class Codes: A61N 1/36014 : External stimulators, e.g. with patch electrodes external pacemakers A61N1/3625
• CPC Class Codes: A61N 1/36021 : for treatment of pain
• CPC Class Codes: A61N 2/002 : in combination with another treatment
• CPC Class Codes: A61N 2/006 : for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 2005/0659 : infrared
• CPC Class Codes: A61N 2007/0073 : using multiple frequencies
• CPC Class Codes: A61N 2007/0078 : with multiple treatment transducers
• CPC Class Codes: A61N 5/0622 : Optical stimulation for exciting neural tissue
• CPC Class Codes: A61N 5/0625 : Warming the body, e.g. hyperthermia treatment
• CPC Class Codes: A61N 5/067 : using laser light
• CPC Class Codes: A61N 7/00 : Ultrasound therapy lithotripsy A61B17/22, A61B17/225; massage using supersonic vibration A61H23/00 ; using ultrasound for introducing media into the body A61M37/0092
• CPC Class Codes: B32B 2274/00 : Thermoplastic elastomer material thermoplastic elastomer fibres B32B2262/0215, thermoplastic elastomer particles B32B2264/0221, thermoplastic elastomer foam B32B2266/0292
• CPC Class Codes: B32B 2307/546 : Flexural strength; Flexion stiffness
• CPC Class Codes: B32B 2307/7166 : Water-soluble, water-dispersible
• CPC Class Codes: B32B 2307/724 : Permeability to gases, adsorption
• CPC Class Codes: B32B 25/08 : of synthetic resin
• CPC Class Codes: B32B 25/20 : comprising silicone rubber
• CPC Class Codes: B32B 2535/00 : Medical equipment, e.g. bandage, prostheses, catheter medical patches B32B2556/00
• CPC Class Codes: B32B 27/08 : of synthetic resin
• CPC Class Codes: B32B 3/08 : characterised by added members at particular parts layer formed of separate pieces of material which are juxtaposed side-by-side B32B3/14, B32B3/18
• CPC Class Codes: B32B 7/12 : using interposed adhesives or interposed materials with bonding properties
• CPC Class Codes: G16H 20/17 : delivered via infusion or injection
• CPC Class Codes: G16H 20/30 : relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
• CPC Class Codes: G16H 50/20 : for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/30 : for calculating health indices; for individual health risk assessment
• CPC Class Codes: G16H 50/50 : for simulation or modelling of medical disorders

Abstract

Systems and methods are described for monitoring an individual and facilitating a motion regimen of the individual. In an aspect, a system includes, but is not limited to, a deformable substrate; a sensor assembly to generate sense signals based on detection of a movement of the body portion and a physiological parameter of the body portion during a motion regimen executed by the individual; a processor including circuitry configured to identify a pain state of the individual based on at least one of the movement or the physiological parameter, and to compare at least one of the pain state, the movement, or the physiological parameter to threshold target values; and a communicator configured to generate communication signals responsive to instruction by the processor, the communication signals associated with comparison between at least one of the pain state, the movement, or the physiological parameter to threshold target values.

Claims

1. A system, comprising:

a deformable substrate configured to conform to a first body portion of an individual subject;

a sensor assembly coupled to the deformable substrate, the sensor assembly including a motion sensor including a proximity sensor configured to detect a movement of the first body portion relative to a second body portion of the individual subject proximate the first body portion, the sensor assembly configured to generate one or more sense signals based on detection of the movement of the first body portion by the motion sensor relative to the second body portion during a motion regimen executed by the individual subject;

a processor operably coupled to the sensor assembly and configured to receive the one or more sense signals, the processor including circuitry configured to identify a pain state of the individual subject based on the movement of the first body portion relative to the second body portion, the circuitry configured to compare at least one of the pain state of the individual subject or the movement of the first body portion relative to the second body portion to one or more threshold target values; and

a communicator configured to generate one or more communication signals responsive to instruction by the processor, the one or more communication signals associated with comparison between at least one of the pain state of the individual subject or the movement of the first body portion relative to the second body portion to one or more threshold target values.

2. The system of claim 1, wherein the one or more threshold target values are associated with a prior execution of the motion regimen by the individual subject.

3. The system of claim 1, wherein the one or more threshold target values correspond to a minimum activity level during execution of the motion regimen.

4. The system of claim 1, wherein the one or more threshold target values correspond to a maximum activity level during execution of the motion regimen and a minimum activity level during execution of the motion regimen.

5. The system of claim 4, wherein the communicator reports the one or more communication signals to at least one of the individual subject or an external device to direct at least one of the pain state of the individual subject or the movement of the first body portion relative to the second body portion between the maximum activity level and the minimum activity level.

6. The system of claim 1, further including at least one effector configured to effect at least one predetermined motion of the first body portion corresponding to the motion regimen.

7. The system of claim 6, wherein the one or more threshold target values correspond to a maximum activity level during execution of the motion regimen and a minimum activity level during execution of the motion regimen.

8. The system of claim 7, wherein the communicator reports the one or more communication signals to the at least one effector to effect at least one predetermined motion of the first body portion corresponding to the motion regimen responsive to at least one of the pain state of the individual subject or the movement of the first body portion relative to the second body portion between the maximum activity level and the minimum activity level.

9. The system of claim 6, wherein the processor is configured to activate the at least one effector to induce the predetermined motion of the first body portion corresponding to the motion regimen responsive to control by the processor.

10. The system of claim 6, wherein the processor is configured to activate the effector to reduce the pain state of the individual subject.

11. The system of claim 1, wherein the communicator is configured to transmit the one or more communication signals to an external location.

12. The system of claim 1, wherein the one or more communication signals correspond to a summary of data stored on a computer memory device, compliance or non-compliance of the individual subject with the motion regimen, or historical progress of the individual subject.

13. The system of claim 1, wherein the motion regimen includes at least one of a rehabilitation regimen, a physical therapy regimen, a training regimen, or a motor skills regimen.

14. The system of claim 1, further including at least one of a receiver, a transceiver, or a transmitter configured to at least one of receive one or more communication signals from an external device or transmit one or more communication signals to the external device.

15. The system of claim 1, wherein the circuitry is configured to identify the pain state of the individual subject responsive to a determination that the movement of the first body portion relative to the second body portion corresponds to at least one of a reduction in velocity of the first body portion, a reduction in muscle activity of a muscle of the first body portion, or an erratic motion of the first body portion.

16. The system of claim 6, wherein the effector includes at least one of an ultrasound transducer, an electrode, a magnetic stimulator, an optical stimulator, a thermal stimulator, an acoustic stimulator, a mechanical stimulator, or a vibration stimulator.

17. The system of claim 14, wherein the processor is configured to at least one of activate the communicator responsive to the one or more communication signals from the external device or prevent activation of the communicator responsive to the one or more communication signals from the external device.

18. The system of claim 1, wherein the sensor assembly is configured to generate one or more identity sense signals associated with at least one physical characteristic of the individual subject, and wherein the processor is configured to at least one of instruct the communicator to generate the one or more communication signals when the one or more identity sense signals correspond to an authorized individual or permit operation of one or more of the sensor assembly or the communicator only when the one or more identity sense signals correspond to an authorized individual.