Needle for biosensor and bio sensor including the same

• US 10,390,707 B2
• Filed: 05/11/2016
• Issued: 08/27/2019
• Est. Priority Date: 05/11/2015
• Status: Active Grant

• Current Assignee: Samsung Electronics Co. Ltd.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: Kim, Kwang-bok, Oh, Young-jae, Cho, Seong-je, Cho, Jae-geol, Cho, Chul-ho, Jung, Sun-tae, Choi, Hyoung-seon
• Primary Examiner(s): Flory, Christopher A
• Application Number:
  US15/152,208
• Publication Number:
  US 20160331238A1
• Time in Patent Office: 1,203 Days
• Field of Search: 600476
• CPC Class Codes: A61B 2562/0233 Special features of optical sensors or probes classified in A61B5/00
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/443 Evaluating skin constituents, e.g. elastin, melanin, water
• CPC Class Codes: A61B 5/444 Evaluating skin marks, e.g. mole, nevi, tumour, scar
• CPC Class Codes: A61B 5/6848 Needles

Abstract

Disclosed is a biosensor needle including a light-transmissive main body having a width that is less than a length so as to be inserted into a testee, and a plurality of metal particles provided at at least a part of the main body and generating a surface enhanced Raman scattering (SERS) effect of light incident through the main body.

Claims

1. A biosensor needle comprising:

a light-transmissive main body having a width that is less than a length of the main body, and is insertable into a testee; and

a plurality of metal particles provided on at least a portion of only an outer surface of the main body configured to contact a testee and generating a surface enhanced Raman scattering effect of light incident through the main body.

2. The biosensor needle of claim 1, wherein the plurality of metal particles comprises at least one of gold particles, silver particles, and copper particles.

3. The biosensor needle of claim 1, wherein the main body comprises a transparent polymer material.

4. The biosensor needle of claim 3, wherein the transparent polymer material is obtained by polymerizing at least one monomer of aniline, EDOT(3,4-ethylenedioxythiophene), pyrrole, N-succinimidyl acrylate, acrylamide, thiophene, aniline-co-pyrrole, amylopectin, carboxymethyl cellulose, dialcohol dimethyl quaterthiophene-co-adipic acid, and methylvinylether/maelic anhydride+ethyleneglycol.

5. The biosensor needle of claim 1, further comprising a biodegradable layer attached onto at least a portion of the surface of the main body and comprising a biodegradable polymer material.

6. The biosensor needle of claim 5, wherein a first end of the biodegradable layer contacts the main body and a second end of the biodegradable layer has a sharp, pointed shape.

7. The biosensor needle of claim 5, wherein the plurality of metal particles are disposed between the biodegradable layer and the main body.

8. The biosensor needle of claim 5, wherein the biodegradable polymer material comprises at least one of polylactic acid, poly(lactic-co-glycolic) acid, poly(caprolactone), polyhydroxyalkanoates, poly(propylene fumarate), polydioxanone, polyglycolide, polyanhydrides, polyacetals, poly(ortho esters), polycarbonates, polyurethanes, and polyphosphazenes.

9. The biosensor needle of claim 5, wherein the main body comprises at least one surface substantially perpendicular to a length direction of the needle.

10. The biosensor needle of claim 9, wherein the biodegradable layer is attached on a surface of the main body that is substantially perpendicular to the length direction of the needle.

11. The biosensor needle of claim 1, wherein the width of the main body is about 40 microns (μ

m) to about 60 μ

m and the length of the main body is about 700 μ

m to about 1400 μ

m.