Temperature-compensated analyte monitoring devices, systems, and methods thereof

• US 10,398,363 B2
• Filed: 01/17/2018
• Issued: 09/03/2019
• Est. Priority Date: 06/16/2011
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Hayter, Gary A., Bernstein, Daniel M., Fennell, Martin J., Love, Michael R., Doniger, Kenneth J., Zhang, Songbiao, Sloan, Mark K., Cho, Hyun, Kunich, Theodore J., Cole, Jean-Pierre, Thomas, Christopher A., Budiman, Erwin S., Li, David L., Cheng, Royce, Hoss, Udo
• Primary Examiner(s): Messersmith, Eric J
• Application Number:
  US15/873,464
• Publication Number:
  US 20180153454A1
• Time in Patent Office: 594 Days
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 2562/0271 Thermal or temperature sensors
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/14503 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors A61B5/1459, A61B5/1464, A61B5/1473, A61B5/1482, A61B5/14865 take precedence
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/7225 Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation A61B5/30, A61B5/316 take precedence; transformers for specific applications H01F38/00; amplifiers H03F

Abstract

Methods of compensating for ambient temperature using a single temperature sensor, the method comprising detecting a first temperature measurement from a temperature sensor; and determining, with a processor, an ambient-compensated temperature from the first temperature measurement using an offset term. The method may also include receiving a sensor signal from an in vivo analyte sensor; and determining, with a processor, a temperature-compensated analyte sensor signal with the ambient-compensated temperature.

Claims

1. A method of compensating for ambient temperature using a single temperature sensor, the method comprising:

detecting a first temperature measurement from a temperature sensor;

receiving a sensor signal from an in vivo analyte sensor; and

determining, with a processor, an ambient-compensated sensor signal-using the first temperature measurement using the formula of I_TC=*k^(32.5−

T), wherein I is the raw sensor current, k is a constant, T is the measured temperature in degrees Celsius, and I_TC is the temperature-compensated analyte sensor signal.

2. The method of claim 1, wherein the analyte is glucose.

3. The method of claim 1, wherein the in vivo analyte sensor is a subcutaneous analyte sensor.

10. The method of claim 1, wherein the constant, k, is 1.07.

4. An analyte monitoring device, comprising:

a housing;

a processor coupled to the housing;

wherein an in vivo analyte sensor is communicably coupled to the processor that produces an analyte sensor signal;

wherein a single temperature sensor is communicably coupled to the processor; and

memory communicably coupled to the processor, wherein the memory includes instructions stored therein that, when executed by the processor, cause the processor to;

receive the sensor signal from an in vivo analyte sensor;

detect a temperature measurement from the single temperature sensor; and

determine an ambient-compensated sensor signal using the temperature measurement using the formula of I_TC=*k^(32.5−

T), wherein I is the raw sensor current, k is a constant, T is the measured temperature in degrees Celsius, and I_TC is the temperature-compensated analyte sensor signal.

5. The analyte monitoring device of claim 4, wherein the analyte is glucose.

6. The analyte monitoring device of claim 4, wherein the in vivo analyte sensor is a subcutaneous analyte sensor.

11. The analyte monitoring device of claim 4, wherein the constant, k, is 1.07.

7. An analyte monitoring system, comprising:

an on-body unit, comprising;

a first processor and first memory communicably coupled to the first processor;

an in vivo analyte sensor communicably coupled to the first processor that produces an analyte sensor signal;

a single temperature sensor communicably coupled to the first processor; and

,

a receiver configured to communicate with the on-body unit, the receiver comprising;

a second processor and second memory communicably coupled to the second processor;

wherein at least one of the first memory and second memory includes instructions stored therein that, when executed by at least one of the first and second processors, cause the at least one first and second processor to;

receive the sensor signal from an in vivo analyte sensor;

detect a temperature measurement from the single temperature sensor; and

determine an ambient-compensated sensor signal using the temperature measurement using the formula of I_TC=*k^(32.5−

T), wherein I is the raw sensor current, k is a constant, T is the measured temperature in degrees Celsius, and I_TC is the temperature-compensated analyte sensor signal.

8. The analyte monitoring system of claim 7, wherein the analyte is glucose.

9. The analyte monitoring system of claim 7, wherein the in vivo analyte sensor is a subcutaneous analyte sensor.

12. The analyte monitoring system of claim 7, wherein the constant, k, is 1.07.