Process for preparing oxycodone compositions

CAFC
  • US 10,407,434 B2
  • Filed: 01/30/2019
  • Issued: 09/10/2019
  • Est. Priority Date: 03/30/2004
  • Status: Active Grant
First Claim
Patent Images

1. A process of purifying oxycodone free base or oxycodone HCl that contains 8α

  • ,14-dihydroxy-7,8-dihydrocodeinone or HCl salt thereof, said process comprising;

    (i) reducing the amount of 8α

    ,14-dihydroxy-7,8-dihydrocodeinone or HCl salt thereof in the oxycodone free base or oxycodone HCl;

    (ii) dissolving the resultant oxycodone free base or oxycodone HCl from step (i) in a suitable recrystallization solvent;

    (iii) cooling the recrystallization solvent to precipitate purified oxycodone free base or oxycodone HCl; and

    (iv) recovering the purified oxycodone free base or oxycodone HCl.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×