Implantable vital sign sensor

• US 10,413,200 B2
• Filed: 03/29/2016
• Issued: 09/17/2019
• Est. Priority Date: 04/06/2015
• Status: Active Grant

• Current Assignee: Thomas Jefferson University (Main Line Health System)
• Original Assignee: Thomas Jefferson University (Main Line Health System)
• Inventors: Joseph, Jeffrey I
• Primary Examiner(s): Winakur, Eric F
• Assistant Examiner(s): Fardanesh, Marjan
• Application Number:
  US15/083,676
• Publication Number:
  US 20160287094A1
• Time in Patent Office: 1,267 Days
• Field of Search: None
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/686 Permanently implanted devices, e.g. pacemakers, other stimulators, biochips A61B5/6861 takes precedence
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61B 5/6879 Means for maintaining contact with the body A61B5/6847 takes precedence
• CPC Class Codes: A61B 5/74 Details of notification to user or communication with user or patient indicating measured values G01D7/00; user input means input or output arrangements for computers G06F3/00
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B

Abstract

An implantable vital sign sensor including a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized to be implanted substantially entirely within the blood vessel wall of the patient. A sensor module configured to measure a blood vessel blood pressure waveform is included, the sensor module having a proximal portion and a distal portion, the distal portion being insertable within the lumen and the proximal portion extending outward from the first open end.

Claims

1. An implantable vital signs measurement device for a patient having a blood vessel with a blood vessel wall, comprising:

a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized and configured to be implanted transmurally within the blood vessel wall of the patient;

a sensor module configured to measure a blood vessel blood pressure waveform, the sensor module having a proximal portion and a distal portion, the distal portion being insertable within the lumen and the proximal portion extending outward from the first open end; and

a sensor module retaining element coupled to the sensor module, the sensor module retaining element configured to retain the sensor module within the first portion and including a plurality of connected and spaced apart links configured to in conjunction with the sensor module, surround an outer circumference of the blood vessel when the distal portion is inserted within the first portion.

2. The device of claim 1, wherein the sensor module includes a pressure transducer having a diaphragm disposed in the distal portion, and wherein the diaphragm is substantially co-planar with the second open end of the housing when the distal portion is inserted within the lumen.

3. The device of claim 1, wherein the housing further includes a second portion orthogonal to the first portion, the second portion being sized to be entirely disposed on an exterior surface of the blood vessel wall when the first portion of the sensor module is implanted within the blood vessel wall.

4. The device of claim 3, wherein the proximal portion of the sensor module is configured to be pressed against the second portion of the housing when the distal portion of the sensor module is inserted within the lumen.

5. The device of claim 1, wherein at least a portion of the proximal portion is configured to seal the first open end and to provide for a predetermined insertion depth when distal portion of the sensor module is inserted within the lumen.

6. The device of claim 1, wherein the first portion of the housing is cylindrical in shape, and wherein the length of the first portion is between 100-1500 microns.

7. The device of claim 6, wherein the length of the first portion is approximately equal to the thickness of at least one of the internal thoracic (mammary) artery, long thoracic artery, aorta, carotid artery, brachial artery, ulnar artery, radial artery, renal artery, splenic artery, iliac artery, and femoral artery of the patient;

or one of the internal thoracic vein, jugular vein, vena cava, renal vein, splenic vein, iliac vein, and femoral vein.

8. The device of claim 1, wherein the proximal portion of the sensor module has a first side and a second side opposite the first side, and the sensor module retaining element has a first end and a second end, and wherein the first end of the sensor module retaining element is affixed to the first side of the sensor module and the second side of the sensor module retaining element is affixed to the second end.

9. The device of claim 1, further including at least one hemoglobin oxygen saturation (SpO2) sensor, the SpO2 pulse oximeter sensor having a light detector, and wherein at least one of the plurality of connected and spaced apart links includes an aperture, and wherein the light detector is configured to be retained within the aperture and face the blood vessel wall.

10. The device of claim 1, wherein the sensor module is removeably insertable within the first portion.

11. The device of claim 1, wherein the sensor module is in electrical communication with a charge storing element, and wherein the charge storing element is configured to be charged inductively through the patient'"'"'s skin.

12. The device of claim 1, wherein the sensor module is configured to measure real-time blood pressure measurements in an ambulatory patient.

13. The device of claim 1, wherein the blood vessel is an artery.