System and method for generating a 2D image from a tomosynthesis data set

• US 10,413,263 B2
• Filed: 06/20/2018
• Issued: 09/17/2019
• Est. Priority Date: 11/27/2002
• Status: Expired due to Fees

• Current Assignee: Hologic Incorporated
• Original Assignee: Hologic Incorporated
• Inventors: Ruth, Christopher, Smith, Andrew P., Stein, Jay
• Primary Examiner(s): Bayat, Ali
• Application Number:
  US16/013,782
• Publication Number:
  US 20190053776A1
• Time in Patent Office: 454 Days
• Field of Search: 382131
• CPC Class Codes: A61B 6/025 Tomosynthesis
• CPC Class Codes: A61B 6/461 Displaying means of special interest
• CPC Class Codes: A61B 6/463 characterised by displaying multiple images or images and diagnostic data on one display
• CPC Class Codes: A61B 6/502 for diagnosis of breast, i.e. mammography
• CPC Class Codes: G06T 11/003 Reconstruction from projections, e.g. tomography
• CPC Class Codes: G06T 11/006 Inverse problem, transformation from projection-space into object-space, e.g. transform methods, back-projection, algebraic methods
• CPC Class Codes: G06T 11/008 Specific post-processing after tomographic reconstruction, e.g. voxelisation, metal artifact correction
• CPC Class Codes: G06T 11/60 Editing figures and text; Combining figures or text
• CPC Class Codes: G06T 19/00 Manipulating 3D models or images for computer graphics
• CPC Class Codes: G06T 19/20 Editing of 3D images, e.g. changing shapes or colours, aligning objects or positioning parts
• CPC Class Codes: G06T 2207/10081 Computed x-ray tomography [CT]
• CPC Class Codes: G06T 2207/10112 Digital tomosynthesis [DTS]
• CPC Class Codes: G06T 2207/20221 Image fusion; Image merging
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 2207/30204 Marker
• CPC Class Codes: G06T 2210/41 Medical
• CPC Class Codes: G06T 2219/2008 Assembling, disassembling

Abstract

A 2D mammogram image is synthesized from at least one of tomosynthesis projection images and/or the tomosynthesis reconstructed image data. In a simplest form, the mammogram may be synthesized by selecting one of the tomosynthesis projection images for display as a synthesized mammogram. Other methods of synthesizing a mammogram include re-projecting and filtering projection data and/or reconstructed data. The synthesized mammogram is advantageously displayed together with at least a portion of the reconstructed data to aid in review of the reconstructed data. The present invention thus provides a familiar image which may be used to facilitate review of a tomosynthesis data set.

Claims

1. A system for generating and displaying a synthesized mammogram, the system comprising:

a computer system, including

a reconstruction engine configured to receive a tomosynthesis data set, the tomosynthesis data set comprising one or more of a plurality of tomosynthesis projection images and/or one or more of a plurality of tomosynthesis reconstructed slices of a patient'"'"'s breast, and

a synthesizer configured to generate a two-dimensional synthesized mammogram from only the tomosynthesis data set, wherein the synthesized mammogram comprises a synthesized two-dimensional image of an entirety of a patient'"'"'s breast that simulates a conventional mammography image; and

a display device operatively coupled with the computer system, wherein the computer system is configured to cause the display device to independently or simultaneously display one or more images from the tomosynthesis data set and the synthesized mammogram.

2. The system of claim 1, the computer system further comprising a Computer Aided Detection (CAD) engine configured to analyze the tomosynthesis data set using computer aided detection.

3. The system of claim 2, wherein the computer system is configured to cause the display device to display a CAD mark on the synthesized mammogram.

4. The system of claim 3, wherein the computer system is configured to cause the display device to display the CAD mark on a displayed image of the tomosynthesis data set.

5. The system of claim 4, wherein an x-y location of the CAD mark on the displayed image of the tomosynthesis data set corresponds to an x-y location of the CAD mark on the synthesized mammogram.

6. The system of claim 4, wherein the computer system is configured to cause the display device to display the CAD mark at a same corresponding x-y location on each image of a plurality successively displayed images of the tomosynthesis data set.

7. The system of claim 6, wherein the successively displayed images of the tomosynthesis data set represent differing z-direction depths of the breast.

8. The system of claim 1, wherein the computer system is configured to cause the display device to simultaneously display an image from the tomosynthesis data set and the synthesized mammogram.

9. The system of claim 8, wherein the displayed image from the tomosynthesis data set matches a pixel spacing of the synthesized mammogram.

10. The system of claim 8, wherein the displayed image from the tomosynthesis data set is a tomosynthesis projection image.

11. The system of claim 8, wherein the displayed image from the tomosynthesis data set is a tomosynthesis reconstructed slice.

12. The system of claim 1, wherein the computer system is configured to cause the display device to display indicia indicating a micro-calcification cluster on the synthesized mammogram.

13. The system of claim 12, wherein the computer system is configured to cause the display device to display the indicia on a displayed image of the tomosynthesis data set.

14. The system of claim 13, wherein an x-y location of the indicia on the displayed image of the tomosynthesis data set corresponds to an x-y location of the indicia on the synthesized mammogram.

15. A computer-implemented method for generating and displaying a synthesized mammogram, the method comprising:

receiving a tomosynthesis data set comprising one or more of a plurality of tomosynthesis projection images and/or one or more of a plurality of tomosynthesis reconstructed slices of a patient'"'"'s breast;

generating a two-dimensional synthesized mammogram from only the tomosynthesis data set, wherein the synthesized mammogram comprises a synthesized two-dimensional image of an entirety of a patient'"'"'s breast that simulates a conventional mammography image, and

independently or simultaneously displaying one or more images from the tomosynthesis data set and the synthesized mammogram.

16. The method of claim 15, further comprising analyzing the tomosynthesis data set using computer aided detection, and displaying a CAD mark on a respective displayed image of the tomosynthesis data set and on the synthesized mammogram.

17. The method of claim 16, wherein an x-y location of the CAD mark on the displayed image of the tomosynthesis data set corresponds to an x-y location of the CAD mark on the synthesized mammogram.

18. The method of claim 17, further comprising displaying the CAD mark at a same corresponding x-y location on each image of a plurality successively displayed images of the tomosynthesis data set, wherein the successively displayed images of the tomosynthesis data set represent differing z-direction depths of the breast.

19. The method of claim 15, further comprising displaying an indicia indicating a micro-calcification cluster on the on a respective displayed image of the tomosynthesis data set and on the synthesized mammogram.

20. The method of claim 19, wherein an x-y location of the indicia on the displayed image of the tomosynthesis data set corresponds to an x-y location of the indicia on the synthesized mammogram.