Method for the treatment of Dravet syndrome

  • US 10,478,441 B2
  • Filed: 02/10/2017
  • Issued: 11/19/2019
  • Est. Priority Date: 05/03/2013
  • Status: Active Grant
First Claim
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1. A method of stimulating 5-HT receptors in the brain of a patient diagnosed with Dravet syndrome, comprising:

  • administering to the patient 0.2 mg/kg/day of fenfluramine or a pharmaceutically acceptable salt thereof; and

    administering to the patient an effective dose of stiripentol or a pharmaceutically acceptable salt thereof;

    whereby 5-HT receptors are stimulated and wherein the 5-HT receptor is in a family of receptors selected from the group consisting of 5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6, and 5-HT7.

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