Biopsy systems for breast computed tomography

  • US 10,492,749 B2
  • Filed: 05/03/2006
  • Issued: 12/03/2019
  • Est. Priority Date: 05/03/2005
  • Status: Active Grant
First Claim
Patent Images

1. A method for breast imaging, comprising the steps of:

  • generating, based on data produced by an x-ray computed tomography (CT) scanner, a three-dimensional volume data set of at least a portion of a breast, wherein a voxel in the three-dimensional volume data set is generated based on x-ray attenuation of a plurality of breast tissue types corresponding to the voxel;

    generating a model of the breast using voxels of the three-dimensional volume data set by assigning biomechanical properties to the plurality of breast tissue types in each voxel of the three-dimensional volume data set;

    generating a compressed volume data set by applying a compression algorithm to the three-dimensional volume data set in a first direction to simulate compression of the breast in the first direction; and

    generating a simulated radiographic compression mammogram projection image corresponding to the three-dimensional volume data set of at least the portion of the breast using cone beam projection on the compressed volume data set, wherein the simulated radiographic compression mammogram projection image is two dimensional mammographic image of the compressed volume data set produced by the compression algorithm based on the biomechanical properties of the plurality of breast tissue types from the three-dimensional volume data set produced by the x-ray CT scanner, wherein the value of a pixel of the simulated radiographic compression mammogram projection image is the result of a summation along a projection path of a ray of the cone beam projection passing through the voxels of the compressed volume data set, wherein at least one value is associated with each voxel of the compressed volume data set, the generating further including;

    transforming contrast property of at least one voxel of the three-dimensional volume data set of at least the portion of the breast to simulate contrast properties of actual radiographic compression mammogram projection images, wherein the contrast property of the at least one voxel is transformed by using linear attenuation coefficients based on composition of the at least one voxel in the three-dimensional volume data set.

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