Composition and method for vancomycin oral liquid

  • US 10,493,028 B2
  • Filed: 10/24/2017
  • Issued: 12/03/2019
  • Est. Priority Date: 03/14/2014
  • Status: Active Grant
First Claim
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1. A non-sterile stable liquid formulation formulated for oral administration, consisting of:

  • (a) 0.1-0.4% w/v anhydrous citric acid,(b) water,(c) 0.1-0.3% w/v sucralose,(d) 0.01-0.1% w/v of a flavoring agent,(e) 0.08-0.2% w/v sodium benzoate,(f) 0.0001-0.0003% w/v of a dye, and(g) vancomycin hydrochloride,wherein the non-sterile stable liquid formulation is homogenous and stable for at least 30 days at ambient and refrigerated temperature conditions and has a pH of 2.5-4.5, and wherein the concentration of vancomycin in the solution is 25-50 mg/ml.

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