Devices capable of fluid sample concentration for extended sensing of analytes
First Claim
1. A sensing device configured to receive a fluid sample, the sensing device comprising:
- one or more first analyte sensors for measuring a characteristic of a first analyte in the fluid sample;
a sample concentrator configured to generate a concentrated form of the fluid sample to increase a first molarity of the first analyte within the fluid sample to a second molarity, wherein the second molarity is at least two times higher than the first molarity, the sample concentrator comprising a membrane that is permeable to liquid and impervious to the first analyte, the membrane having a first surface adjacent to the fluid sample and a second surface opposite the fluid sample;
a collector for collecting the fluid sample from a body of a sensing device wearer;
a channel for transporting the fluid sample from the collector to the sample concentrator, to the one or more sensors, and away from the one or more sensors.
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Accused Products
Abstract
The disclosed invention provides a fluid sensing device and method capable of collecting a fluid sample, concentrating the sample with respect to one or more target analytes, and measuring the target analyte(s) in the concentrated sample. The invention is also capable of determining the change in molarity of the fluid sample with respect to the target analyte(s), as the sample is concentrated by the device. The invention further includes a method for using a fluid sensing device to concentrate a fluid sample with respect to one or more target analytes. The disclosed method further includes the ability to correlate the measured target analyte concentration to a physiological condition of a device wearer, or of a fluid source.
130 Citations
10 Claims
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1. A sensing device configured to receive a fluid sample, the sensing device comprising:
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one or more first analyte sensors for measuring a characteristic of a first analyte in the fluid sample; a sample concentrator configured to generate a concentrated form of the fluid sample to increase a first molarity of the first analyte within the fluid sample to a second molarity, wherein the second molarity is at least two times higher than the first molarity, the sample concentrator comprising a membrane that is permeable to liquid and impervious to the first analyte, the membrane having a first surface adjacent to the fluid sample and a second surface opposite the fluid sample; a collector for collecting the fluid sample from a body of a sensing device wearer; a channel for transporting the fluid sample from the collector to the sample concentrator, to the one or more sensors, and away from the one or more sensors. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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Specification