Nucleic acids encoding IL-8 antibodies

  • US 10,519,229 B2
  • Filed: 05/10/2018
  • Issued: 12/31/2019
  • Est. Priority Date: 02/05/2015
  • Status: Active Grant
First Claim
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1. An isolated nucleic acid encoding an anti-IL-8 antibody which comprises a heavy chain variable region (VH) and a light chain variable region (VL), wherein(a) the VH comprises:

  • (i) a HVR-H1 comprising the amino acid sequence of SEQ ID NO;

    67,(ii) a HVR-H2 comprising the amino acid sequence of SEQ ID NO;

    73,(iii) a HVR-H3 comprising the amino acid sequence of SEQ ID NO;

    74; and

    (b) the VL comprises;

    (i) a HVR-L1 comprising the amino acid sequence of SEQ ID NO;

    70,(ii) a HVR-L2 comprising the amino acid sequence of SEQ ID NO;

    75, and(iii) a HVR-L3 comprising the amino acid sequence of SEQ ID NO;

    76.

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